Category Archives: Prevention, Engagement and Care Cascade
A literature review on the adherence to screening guidelines for latent tuberculosis infection among persons living with HIV
Human immunodeficiency virus (HIV) infection increases the risk of reactivation of latent tuberculosis infection (LTBI). Although antiretroviral therapy decreases the progression of LTBI to tuberculosis disease (TBD), persons living with...
Machine learning prediction models for clinical management of blood-borne viral infections: A systematic review of current applications and future impact
BACKGROUND: Machine learning (ML) prediction models to support clinical management of blood-borne viral infections are becoming increasingly abundant in medical literature, with a number of competing models being developed for...
Adherence to oral pre-exposure prophylaxis intervention by transgender women: A systematic review
Prevalence of human immunodeficiency virus (HIV) is higher in transgender populations. Pre-exposure prophylaxis (PrEP) intervention is successful in reducing HIV acquisition. We aimed to investigate the adherence to oral PrEP...
Adherence to antiretroviral therapy among HIV patients in Ghana: A systematic review and meta-analysis
Maintaining a high level of adherence to antiretroviral therapy (ART) is critical to limiting rapid viral replication, drug resistance, and viral transmission. However, ART adherence remains a major challenge in...
Virologic response to Dolutegravir plus Lamivudine in people with suppressed human immunodeficiency virus type 1 and historical M184V/I: A systematic literature review and meta-analysis
BACKGROUND: To investigate the impact of the M184V/I mutation on virologic response to dolutegravir plus lamivudine (DTG + 3TC) in suppressed-switch populations, a meta-analysis was performed using virologic outcomes from...
Health facility-based interventions and the uptake of contraception among people living with HIV: A systematic review & meta-analysis
BACKGROUND OBJECTIVES: The prong 2 of 4 prong strategy introduced by the World Health Organization aims at averting unintended pregnancies among people living with HIV (PLHIV). This systematic review aimed...
Adherence, adverse drug reactions, and discontinuation associated with adverse drug reactions of HIV post-exposure prophylaxis: A meta-analysis based on cohort studies
Objective: Evaluate the profiles of post-exposure prophylaxis (PEP) adherence, adverse drug reactions (ADRs), and discontinuation associated with ADRs to provide information for further PEP program improvement and increase adherence to...
HIV, hepatitis B & C in people who inject drugs in India: A systematic review of regional heterogeneity & overview of opioid substitution treatment
BACKGROUND OBJECTIVES: This systematic review evaluates the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) burden among people who inject drugs (PWIDs) in India. In...
A scoping review of biobehavioural interventions to improve PrEP continuum of care in Latin America
According to the literature, biobehavioural interventions or combined strategies would reduce the risk of HIV infection by more than 7,000 new cases each day, which would contribute to the battle...
The impact of contemporary antiretroviral drugs on atherosclerosis and its complications in people living with HIV: A systematic review
With thWith the advent of modern antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection has been modified into a chronic manageable condition, prolonging the lifespan of people living with HIV...
Recent progress in synthesis, POM analyses and SAR of Coumarin-hybrids as potential anti-HIV agents—A Mini Review
The human immunodeficiency virus (HIV) is the primary cause of acquired immune deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms and procedures have been pursued to synthesise...
