Category Archives: Prevention, Engagement and Care Cascade

Impact of combined antiretroviral therapy on metabolic syndrome components in adult people living with HIV: A literature review

2022

The development of metabolic derangements as a result of HIV treatment has been an important area of research since the introduction of zidovudine in the 1980’s. Antiretroviral therapy has intensely...

Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression

2022

Despite significant advances in the treatment and care of people with HIV (PWH), several challenges remain in our understanding of disease pathogenesis to improve patient care. HIV infection can modify...

HIV-1 genetic diversity a challenge for AIDS vaccine development: A retrospective bibliometric analysis

2022

Background: Despite recent advances in human immunodeficiency virus-1 (HIV-1) prevention, a fast, safe, and effective vaccine will probably be necessary to end the HIV/AIDS pandemic. This study was conducted to evaluate...

Awareness and sse of post-exposure prophylaxis for HIV prevention among men who have sex with men: A systematic review and meta-analysis

2022

Background: The use of post-exposure prophylaxis (PEP) is effective in reducing HIV risk, but it is underused by men who have sex with men (MSM) due to certain psychological and...

Loco-regional treatments for hepatocellular carcinoma in people living with HIV

2022

Hepatocellular carcinoma (HCC) accounts for approximately 75–90% of primary liver cancers and is the sixth most common cancer and the third leading cause of cancer-related deaths worldwide. In the HIV-positive...

Understanding the epidemiological HIV risk factors and underlying risk context for youth residing in or originating from the Middle East and North Africa (MENA) region: A scoping review of the literature

2022

INTRODUCTION: HIV is the second leading cause of death among young people globally, and adolescents are the only group where HIV mortality is not declining. Middle East and North Africa...

Microbiota-meditated immunity abnormalities facilitate hepatitis B virus co-infection in people living with HIV: A review

2022

Hepatitis B virus (HBV) co-infection is fairly common in people living with HIV (PLWH) and affects millions of people worldwide. Identical transmission routes and HIV-induced immune suppression have been assumed...

Drug-drug interactions in people living with HIV at risk of hepatic and renal impairment: Current status and future perspectives

2022

Despite the advancement of antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV), drug-drug interactions (DDIs) remain a relevant clinical issue for people living with HIV receiving ART....

Safety of antiretroviral therapy in the treatment of HIV/AIDS in children: Systematic review and meta-analysis

2021

The safety of using different antiretroviral therapies (ART) in pediatric HIV/AIDS patients is not well-established. Therefore, this study aimed to assess the safety of ART in children. A systematic review...

How does HIV persist under antiretroviral therapy: A review of the evidence

2021

HIV-1 is a retrovirus capable of establishing viral reservoirs that remain stable for extended periods under suppressive antiretroviral therapy (ART). Immune dysfunction and latency are well known to contribute to...

Combinatorial strategies for long-term control of HIV infection

2021

AIDS is a disease caused by a chronic infection of HIV. Recently, long-term control of HIV infection has been demonstrated through the bone marrow transplantation of hematopoietic stem cells (HSC),...

Potential immune modulatory effect of vitamin D in HIV infection: A review

2021

Vitamin D is a fat soluble hormone that is majorly involved in the classical function of calcium and phosphorus hemostasis and bone mineralization as well non classical functions of immune...

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