Category Archives: Prevention, Engagement and Care Cascade
Assessing bone mineral density in children and adolescents living with HIV and on treatment with tenofovir disoproxil fumarate: A systematic review
OBJECTIVE: To investigate the impact of tenofovir disoproxil fumarate on bone mineral density and bone mineral content in children and adolescents infected with the human immunodeficiency virus. DATA SOURCE: The...
Demand creation and retention strategies for oral pre-exposure prophylaxis for HIV prevention among men who have sex with men and transgender women: A systematic review and meta-analysis
Background Men who have sex with men (MSM) and transgender women (TGW) have a disproportionately higher risk of human immunodeficiency virus (HIV) infection than other groups. Oral HIV pre-exposure prophylaxis...
Non-pharmacological interventions for improving sleep in people living with HIV: A systematic narrative review
BACKGROUND: Sleep disturbances are common in people living with Human Immunodeficiency Virus (HIV) and may lead to poor adherence to antiretroviral therapy and worsen HIV symptom severity. Due to the...
Adherence, adverse drug reactions, and discontinuation associated with adverse drug reactions of HIV post-exposure prophylaxis: A meta-analysis based on cohort studies
Objective: Evaluate the profiles of post-exposure prophylaxis (PEP) adherence, adverse drug reactions (ADRs), and discontinuation associated with ADRs to provide information for further PEP program improvement and increase adherence to...
A scoping review of biobehavioural interventions to improve PrEP continuum of care in Latin America
According to the literature, biobehavioural interventions or combined strategies would reduce the risk of HIV infection by more than 7,000 new cases each day, which would contribute to the battle...
Adherence to oral pre-exposure prophylaxis intervention by transgender women: A systematic review
Prevalence of human immunodeficiency virus (HIV) is higher in transgender populations. Pre-exposure prophylaxis (PrEP) intervention is successful in reducing HIV acquisition. We aimed to investigate the adherence to oral PrEP...
The impact of contemporary antiretroviral drugs on atherosclerosis and its complications in people living with HIV: A systematic review
With thWith the advent of modern antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection has been modified into a chronic manageable condition, prolonging the lifespan of people living with HIV...
Recent progress in synthesis, POM analyses and SAR of Coumarin-hybrids as potential anti-HIV agents—A Mini Review
The human immunodeficiency virus (HIV) is the primary cause of acquired immune deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms and procedures have been pursued to synthesise...
Machine learning prediction models for clinical management of blood-borne viral infections: A systematic review of current applications and future impact
BACKGROUND: Machine learning (ML) prediction models to support clinical management of blood-borne viral infections are becoming increasingly abundant in medical literature, with a number of competing models being developed for...
Adherence to antiretroviral therapy among HIV patients in Ghana: A systematic review and meta-analysis
Maintaining a high level of adherence to antiretroviral therapy (ART) is critical to limiting rapid viral replication, drug resistance, and viral transmission. However, ART adherence remains a major challenge in...
Virologic response to Dolutegravir plus Lamivudine in people with suppressed human immunodeficiency virus type 1 and historical M184V/I: A systematic literature review and meta-analysis
BACKGROUND: To investigate the impact of the M184V/I mutation on virologic response to dolutegravir plus lamivudine (DTG + 3TC) in suppressed-switch populations, a meta-analysis was performed using virologic outcomes from...
