Category Archives: Prevention, Engagement and Care Cascade

Low-level HIV viremia: Definitions, predictors, mechanisms, and clinical outcomes

2022

Key take-home messages The definitions of optimal viral suppression, low-level viremia, blips, virologic failure, and recommended management approaches to low-level viremia vary greatly across studies and clinical guidelines. There is...

HIV response interventions that integrate HIV molecular cluster and social network analysis: A systematic review

2021

Due to improved efficiency and reduced cost of viral sequencing, molecular cluster analysis can be feasibly utilized alongside existing human immunodeficiency virus (HIV) prevention strategies. The goal of this paper...

Meta-analysis on nicotine’s modulation of HIV-associated dementia

2021

HIV-Associated Dementia (HAD) is a significant comorbidity that many HIV-patients face. Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine’s impact...

Integrating HIV services and other health services: A systematic review and meta-analysis

2021

BACKGROUND: Integration of HIV services with other health services has been proposed as an important strategy to boost the sustainability of the global HIV response. We conducted a systematic and...

Mobile health interventions for HIV/STI prevention among youth in low- and middle-income countries (LMICs): A systematic review of studies reporting implementation outcomes

2021

Background Advances and proliferation of technologies such as mobile phones may provide opportunities to improve access to HIV/STI services and reach young people with high risk for HIV and STI....

Contraception values and preferences of people living with HIV: A systematic review

2021

OBJECTIVE: Attention to the contraception values and preferences of those living with HIV is essential to meeting their reproductive rights and health needs. We systematically reviewed the literature on contraception...

Validated HIV knowledge scales for use with adults and adolescents: A systematic review

2021

HIV knowledge—the information a person possesses about HIV—is essential for the prevention and management of HIV. Therefore, the accurate measurement of HIV knowledge is important for both science and practice....

Storytelling as a research tool used to explore insights and as an intervention in public health: A systematic narrative review

2021

Objectives: Studies of storytelling (ST) used as a research tool to extract information and/or as an intervention to effect change in the public knowledge, attitudes, and behavior/practice (KAB/P) were sought...

Safety of tenofovir disoproxil fumarate for pregnant women facing the coronavirus disease 2019 pandemic

2021

We assessed the teratogenicity of tenofovir, a human immunodeficiency virus (HIV) drug similar to remdesivir that is currently being evaluated for the treatment of coronavirus disease 2019 (COVID-19). Using US...

Current approaches to HIV vaccine development: A narrative review

2021

INTRODUCTION: The development of an effective vaccine to protect against HIV is a longstanding global health need complicated by challenges inherent to HIV biology and to the execution of vaccine...

HIV protease inhibitors and insulin sensitivity: A systematic review and meta-analysis of randomized controlled trials

2021

Background: Protease inhibitors (PIs) are believed to affect insulin sensitivity. We aimed to analyze the effect of PIs on insulin sensitivity and the onset of diabetes mellitus (DM) in patients with...

Pre-exposure prophylaxis uptake, adherence, and persistence: A narrative review of interventions in the U.S

2021

Since 2012, HIV pre-exposure prophylaxis (PrEP) has been available to prevent HIV transmission; yet, uptake, adherence, and persistence to PrEP have been suboptimal. This narrative review examines the latest interventions...

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