Category Archives: Prevention, Engagement and Care Cascade
Systematic review of infodemiology studies using artificial intelligence: Social media posts on HIV preexposure prophylaxis
OBJECTIVES: To explore how artificial intelligence (AI) can enhance infodemiology, which distributes and scans information in the electronic medium, to process social media posts for HIV preexposure prophylaxis (PrEP). DESIGN:...
Machine learning for personalized risk assessment of HIV, syphilis, gonorrhoea and chlamydia: A systematic review and meta-analysis
Background Machine learning (ML) shows promise for sexually transmitted infection (STI) risk prediction, but systematic evidence of its effectiveness remains fragmented. Methods We systematically searched six electronic databases, three preprint...
Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: A systematic review and meta-analysis
Background Although a growing body of evidence supports zero risk of sexual HIV transmission from a person with sustained virological suppression, known as U=U (undetectable equals untransmittable), data have been...
Evaluating predictive performance, validity, and applicability of machine learning models for predicting HIV treatment interruption: A systematic review
Background HIV treatment interruption remains a significant barrier to achieving global HIV/AIDS control goals. Machine learning (ML) models offer potential for predicting treatment interruption by leveraging large clinical data. Understanding...
HIV infection and antiretroviral therapy impair liver function in people living with HIV: Systematic review and meta-analysis
Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...
HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis
Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...
Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents
Background Despite the effectiveness of antiretroviral treatment (ART) in reducing morbidity and mortality, children and adolescents with co-infections face an elevated risk of death due to their young age and...
Undetectable = Untransmittable: A cross-population systematic review and meta-analysis on awareness and acceptance
The Undetectable = Untransmittable (U=U) message is a cornerstone of HIV-related public health communication, yet global levels of awareness and acceptance remain unclear across key populations. This study aimed to...
Growth patterns of HIV-exposed and -unexposed infants in African countries: A systematic review and meta-analysis
Background/Objectives: The purpose of this study is to understand the prevalence and odds of poor growth patterns among HIV-exposed but uninfected (HEU) versus HIV-unexposed (HUU) infants in the era of antiretroviral...
HIV-1 drug resistance in children and implications for pediatric treatment strategies: A systematic review and meta-analysis
Introduction Failure in the prevention of mother-to-child HIV transmission (PMTCT) and pediatric treatment challenges led to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children with HIV (CWHIV)....
The association between HIV infection and carotid intima-media thickness in the era of antiretroviral therapy: A meta-analysis
Atherosclerosis remains a leading cause of mortality globally, and this is worse in people living with HIV (PLHIV). While the administration of antiretroviral therapy (ART) in this population has significant...
