Category Archives: Prevention, Engagement and Care Cascade
Vaccination coverage among individuals receiving HIV pre-exposure prophylaxis (PrEP): A systematic review and meta-analysis
Objective: This study aimed to assess vaccination coverage among individuals receiving HIV pre-exposure prophylaxis (PrEP). Methods: A systematic review and meta-analysis were conducted following PRISMA guidelines. PubMed, Scopus, and Web of Science...
Barriers and facilitators to preventing mother-to-child transmission of HIV in sub-Saharan Africa: A scoping review
Women account for 59% of human immunodeficiency virus (HIV) infection cases in sub-Saharan Africa. This impacts the increase in mother-to-child HIV transmission rates and presents challenges to preventive care for...
The reasons of late diagnosis in patients with HIV/AIDS: A meta-synthesis
PURPOSE: To comprehensively integrate qualitative findings on the reasons for late diagnosis in HIV/AIDS patients and to encourage timely clinic consultations for advisory purposes. METHODS: A qualitative systematic review utilizing...
Broadly neutralizing antibodies for HIV therapy in clinical trials: A systematic review
Background: Lifelong daily antiretroviral therapy (ART) effectively suppresses human immunodeficiency virus type 1 (HIV-1) replication but does not eradicate the virus, underscoring the urgent need for long-acting antivirals and functional cure...
Incidence of occupational HIV seroconversion among healthcare workers: A systematic review and meta-analysis
Background Healthcare workers (HCWs) may be at elevated risk of HIV infection due to the global HIV burden and frequent occupational exposure to blood and body fluids (BBF). This systematic...
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications
Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...
Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis
BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...
Retention in care among women with HIV: A systematic review of treatment continuity during pregnancy and postpartum
Introduction Pregnant women with HIV are at risk of reduced engagement in HIV care during pregnancy and postpartum. Retention in care, defined as continuous engagement in HIV-related treatment and follow-up,...
Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis
Background Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral and bacterial pathogens (HIV, hepatitis B and C viruses, Treponema pallidum)...
Barriers and facilitators to healthcare access among Sub-Saharan African migrants in Europe: A scoping review
Background Sub-Saharan African (SSA) migrants represent a significant and growing proportion of Europe’s diverse migrant population; yet face substantial barriers in accessing healthcare services. Understanding these barriers is essential for...
Burden of malaria-HIV coinfection and associated adverse outcomes in Ethiopia: A systematic review and meta-analysis
Background The co-occurrence of malaria and HIV represents a significant health crisis in sub-Saharan Africa, particularly in Ethiopia, where both diseases are prevalent. This synergistic burden aggravates health inequalities, strains...
