Category Archives: Prevention, Engagement and Care Cascade
Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus
Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...
The prevalence of HIV-infected patients with virological suppression but a CD4+ T-cell count of ≤ 200 cells/mm3 after highly active antiretroviral therapy initiation: A meta-analysis
Highly active antiretroviral therapy (HAART) strongly inhibits HIV replication. However, many patients show suboptimal immune recovery (SIR), as defined by virological suppression (i.e. low viral load) with a CD4+ T-cell count...
A systematic review and meta-analysis to estimate the time from HIV infection to diagnosis for people with HIV
Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred...
Barriers and facilitators to HIV pre-exposure prophylaxis uptake, adherence, and persistence among transgender populations in the United States: A systematic review
HIV pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV; however, PrEP use among transgender individuals remains low. We conducted a systematic review to identify barriers and facilitators to PrEP...
Factors associated with post-treatment control of viral load in HIV-infected patients: A systematic review and meta-analysis
BACKGROUND: This study aimed to investigate the factors associated with maintenance of viral suppression after antiretroviral therapy (ART) discontinuation. METHODS: Databases were searched for studies published between 1 January, 2011,...
Quantitative methods used to evaluate impact of combination HIV prevention intervention: A methodological systematic review
Combination HIV prevention aims to provide the right mix of biomedical, behavioral and structural interventions, and is considered the best approach to curb the HIV pandemic. The impact evaluation of...
Perinatal outcomes associated with combination antiretroviral therapy compared with monotherapy
Objectives: Increasing numbers of women living with HIV (WLHIV) worldwide receive combination antiretroviral therapy (cART) during pregnancy. We aimed to assess the risk of adverse perinatal outcomes in pregnant WLHIV receiving...
Determining the screening frequency for sexually transmitted infections for people who use HIV pre-exposure prophylaxis: A systematic review and meta-analysis
Background: Although the World Health Organization (WHO) recommends ‘frequent’ screening of sexually transmitted infections (STI) for people who use pre-exposure prophylaxis (PrEP) for HIV, there is no evidence for optimal frequency....
The role of women in promoting voluntary medical male circumcision uptake: Literature review
Voluntary medical male circumcision (VMMC) is a global strategy for reducing female-to-male sexual transmission of HIV. Women whose partners are circumcised benefit from a reduced risk of contracting other sexually...
Applying behavioural insights to HIV prevention and management: A scoping review
PURPOSE OF REVIEW: This scoping review summarises the literature on HIV prevention and management interventions utilizing behavioural economic principles encapsulated in the MINDSPACE framework. RECENT FINDINGS: MINDSPACE is an acronym...
