Category Archives: Prevention, Engagement and Care Cascade

Counselling behavioural interventions for HIV, STI and viral hepatitis among key populations: A systematic review of effectiveness, values and preferences, and cost studies

2023

INTRODUCTION: Key populations (sex workers, men who have sex with men, people who inject drugs, people in prisons and other closed settings, and trans and gender diverse individuals) are disproportionately...

Cutting edge strategies for screening of novel anti-HIV drug candidates against HIV infection: A concise overview of cell based assays

2023

The advent of Highly Active Antiretroviral Therapy has majorly contributed towards reducing the morbidity and mortality associated with HIV infected people, thus improving the quality of their life. Still, the...

HIV prevention intervention-related research with adult, sexual minority hispanic men in the United States: A systematic review

2023

The systematic review describes aims to synthesize the HIV prevention intervention-related research conducted among adult, US sexual minority Hispanic men since 2012. Following PRISMA guidelines, 15 articles representing 14 studies...

Serological response following COVID-19 vaccines in patients living with HIV: A dose-response meta-analysis

2023

To quantify the pooled rate and risk ratio of seroconversion following the uncomplete, complete, or booster dose of COVID-19 vaccines in patients living with HIV. PubMed, Embase and Cochrane library...

Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus

2023

BACKGROUND: Hepatitis B virus (HBV)-human Immunodeficiency virus (HIV) co-infection promotes an aggressive disease course of HBV infection. In the only available non-Cochrane systematic review on antiviral therapy during pregnancy for...

Weight and metabolic outcomes in naïve HIV patients treated with integrase inhibitor-based antiretroviral therapy: A systematic review and meta-analysis

2023

Background: The use of integrase inhibitor-based antiretroviral therapy could be associated with worse weight and metabolic outcomes in patients with HIV infection. Methods: PubMed, EMBASE, and Scopus were searched from inception to...

Barriers and facilitators to HIV pre-exposure prophylaxis for cisgender and transgender women in the UK

2023

Uptake of oral HIV pre-exposure prophylaxis (PrEP) among cisgender and transgender women in the UK has been low. In this Review, we explore the barriers and facilitators to PrEP access...

Assessing PrEP messaging and communication: A review of the qualitative literature

2023

Pre-exposure prophylaxis (PrEP) is a biomedical HIV prevention intervention approved by the FDA in 2012. Nevertheless, most sexual minority men (SMM) who could benefit from its use are not currently...

A comprehensive overview on the role of phytocompounds in human immunodeficiency virus treatment

2023

Acquired immune deficiency syndrome (AIDS) is a worldwide epidemic caused by human immunodeficiency virus (HIV) infection. Newer medicines for eliminating the viral reservoir and eradicating the virus are urgently needed....

Methodological and reporting quality of non-inferiority randomised controlled trials comparing antiretroviral therapies: A systematic review

2023

Background: It is unclear whether the reporting quality of antiretroviral non-inferiority randomised controlled trials (ARV NI-RCTs) has improved since the CONSORT guideline release in 2006. The primary objective of this systematic...

Cost-effectiveness of anti-retroviral adherence interventions for people living with HIV: A systematic review of decision analytical models

2023

BACKGROUND: Although safe and effective anti-retrovirals (ARVs) are readily available, non-adherence to ARVs is highly prevalent among people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Different adherence-improving interventions have...

Barriers to pre-exposure prophylaxis (PrEP) use for HIV: An integrative review

2023

OBJECTIVES: to identify and synthesize scientific evidence on the barriers and difficulties for Pre-exposure Prophylaxis (PrEP) use and compliance for HIV. METHODS: an integrative literature review, using the MEDLINE/PubMed, Cumulative...

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