Category Archives: Prevention, Engagement and Care Cascade
Clinical impact of pretreatment human immunodeficiency virus drug resistance in people initiating nonnucleoside reverse transcriptase inhibitor-containing antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Increased access to antiretroviral therapy (ART) has resulted in rising levels of pretreatment human immunodeficiency virus drug resistance (PDR). This is the first systematic review and meta-analysis to assess...
Recruitment of US adolescents and young adults (AYA) into human immunodeficiency virus (HIV)-related behavioral research studies: A scoping review
PURPOSE OF REVIEW: The objective of this scoping review was to examine the range of published evidence on recruitment approaches and outcomes of US adolescents and young adults (AYA) ages...
The LAIs are coming! implementation science considerations for long-acting injectable antiretroviral therapy in the United States: A scoping review
Long-acting injectable antiretroviral therapy (LAI-ART) is one of the latest advancements in HIV control with the potential to overcome oral ART barriers to adherence. The objective of this article is...
Comparing the effects of HIV self-testing to standard HIV testing for key populations: A systematic review and meta-analysis
BACKGROUND: We update a previous systematic review to inform new World Health Organization HIV self-testing (HIVST) recommendations. We compared the effects of HIVST to standard HIV testing services to understand...
Rapid evidence review of harm reduction interventions and messaging for people who inject drugs during pandemic events: Implications for the ongoing COVID-19 response
BACKGROUND: People who inject drugs are at increased health risk in a pandemic due to their greater susceptibility to severe disease and as a consequence of the restrictions put in...
Psychosocial support interventions for improved adherence and retention in ART care for young people living with HIV (10-24 years): A scoping review
Background: Mental health disorders such as high levels of anxiety, isolation, depression and suicide ideation reported among young people living with HIV (10-24 years;YPLHIV) contribute significantly to poor medication adherence...
Interactive digital interventions for prevention of sexually transmitted HIV: Systematic review and meta-analyses
BACKGROUND: Digital technology offers good opportunities for HIV prevention. This systematic review assesses the effectiveness of interactive digital interventions (IDIs) for prevention of sexually transmitted HIV. METHODS: We conducted a...
Interventions to improve daily medication use among adolescents and young adults: What can we learn for youth pre-exposure prophylaxis services?
OBJECTIVE: Oral pre-exposure prophylaxis (PrEP) is an important HIV prevention method and studies have shown that young people ages 15-24 have difficulty adhering to daily PrEP. The field of PrEP...
Retention in care and viral suppression in differentiated service delivery models for HIV treatment delivery in sub-Saharan Africa: A rapid systematic review
INTRODUCTION: Differentiated service delivery (DSD) models for antiretroviral treatment (ART) for HIV are being scaled up in the expectation that they will better meet the needs of patients, improve the...
The magnitude of adherence to option B plus program and associated factors among women in eastern African countries: A systematic review and meta-analysis
Background: Despite coverage and benefits associated with the prevention of mothers to child transmission (PMTCT) services, mothers’ adherence to option B plus is still a challenge. Though few primary studies...
What do we know about patient-provider interactions in sub-Saharan Africa? A scoping review
INTRODUCTION: patient-centred care has become a rallying call for improving quality and access to care in countries where health system responsiveness and satisfaction with health services remain low. Understanding patient-provider...
Technology-Based Interventions to Increase Point-of-Care HIV Testing and Linkage to Care Among Youth in the US: A Systematic Review
HIV testing rates remain low among youth ages 13-24 in the US, with only 55% of HIV-positive youth aware of their serostatus. We conducted a systematic review to assess the...
