Category Archives: Prevention, Engagement and Care Cascade
How has HIV pre-exposure prophylaxis (PrEP) changed sex? A review of research in a new era of bio-behavioral HIV prevention
In 2012, the U.S. FDA approved the first drug for use as HIV Pre-Exposure Prophylaxis (PrEP), which is nearly 99% effective when taken as prescribed. Although the manifest function of...
A scoping review of sexual transmission related HIV research among key populations in Malaysia: Implications for interventions across the HIV care cascade
The Malaysian government has committed to ‘Fast Tracking the HIV Response’ to achieve UNAIDS 2030 targets to end AIDS. The epidemic is concentrated among key populations and has shifted from...
Low-level HIV viremia: Definitions, predictors, mechanisms, and clinical outcomes
Key take-home messages The definitions of optimal viral suppression, low-level viremia, blips, virologic failure, and recommended management approaches to low-level viremia vary greatly across studies and clinical guidelines. There is...
Storytelling as a research tool used to explore insights and as an intervention in public health: A systematic narrative review
Objectives: Studies of storytelling (ST) used as a research tool to extract information and/or as an intervention to effect change in the public knowledge, attitudes, and behavior/practice (KAB/P) were sought...
Safety of tenofovir disoproxil fumarate for pregnant women facing the coronavirus disease 2019 pandemic
We assessed the teratogenicity of tenofovir, a human immunodeficiency virus (HIV) drug similar to remdesivir that is currently being evaluated for the treatment of coronavirus disease 2019 (COVID-19). Using US...
HIV protease inhibitors and insulin sensitivity: A systematic review and meta-analysis of randomized controlled trials
Background: Protease inhibitors (PIs) are believed to affect insulin sensitivity. We aimed to analyze the effect of PIs on insulin sensitivity and the onset of diabetes mellitus (DM) in patients with...
Pre-exposure prophylaxis uptake, adherence, and persistence: A narrative review of interventions in the U.S
Since 2012, HIV pre-exposure prophylaxis (PrEP) has been available to prevent HIV transmission; yet, uptake, adherence, and persistence to PrEP have been suboptimal. This narrative review examines the latest interventions...
A scoping review investigating relationships between depression, anxiety, and the PrEP care continuum in the United States
Men who have sex with men and transgender women in the United States are at increased risk for HIV and may benefit from pre-exposure prophylaxis (PrEP), a once-a-day pill to...
HIV response interventions that integrate HIV molecular cluster and social network analysis: A systematic review
Due to improved efficiency and reduced cost of viral sequencing, molecular cluster analysis can be feasibly utilized alongside existing human immunodeficiency virus (HIV) prevention strategies. The goal of this paper...
Meta-analysis on nicotine’s modulation of HIV-associated dementia
HIV-Associated Dementia (HAD) is a significant comorbidity that many HIV-patients face. Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine’s impact...
