Category Archives: Prevention, Engagement and Care Cascade

How has HIV pre-exposure prophylaxis (PrEP) changed sex? A review of research in a new era of bio-behavioral HIV prevention

2021

In 2012, the U.S. FDA approved the first drug for use as HIV Pre-Exposure Prophylaxis (PrEP), which is nearly 99% effective when taken as prescribed. Although the manifest function of...

A scoping review of sexual transmission related HIV research among key populations in Malaysia: Implications for interventions across the HIV care cascade

2021

The Malaysian government has committed to ‘Fast Tracking the HIV Response’ to achieve UNAIDS 2030 targets to end AIDS. The epidemic is concentrated among key populations and has shifted from...

Initiation of HIV pre-exposure prophylaxis in adolescents and young adults: Barriers and opportunities

2021

BACKGROUND: Adolescents and young adults (AYA) ages 13 to 24 years comprise a quarter of the new HIV diagnoses in the United States. Lack of access to HIV-preventive biomedical tools...

Low-level HIV viremia: Definitions, predictors, mechanisms, and clinical outcomes

2022

Key take-home messages The definitions of optimal viral suppression, low-level viremia, blips, virologic failure, and recommended management approaches to low-level viremia vary greatly across studies and clinical guidelines. There is...

Integrating HIV services and other health services: A systematic review and meta-analysis

2021

BACKGROUND: Integration of HIV services with other health services has been proposed as an important strategy to boost the sustainability of the global HIV response. We conducted a systematic and...

Mobile health interventions for HIV/STI prevention among youth in low- and middle-income countries (LMICs): A systematic review of studies reporting implementation outcomes

2021

Background Advances and proliferation of technologies such as mobile phones may provide opportunities to improve access to HIV/STI services and reach young people with high risk for HIV and STI....

Contraception values and preferences of people living with HIV: A systematic review

2021

OBJECTIVE: Attention to the contraception values and preferences of those living with HIV is essential to meeting their reproductive rights and health needs. We systematically reviewed the literature on contraception...

Validated HIV knowledge scales for use with adults and adolescents: A systematic review

2021

HIV knowledge—the information a person possesses about HIV—is essential for the prevention and management of HIV. Therefore, the accurate measurement of HIV knowledge is important for both science and practice....

Storytelling as a research tool used to explore insights and as an intervention in public health: A systematic narrative review

2021

Objectives: Studies of storytelling (ST) used as a research tool to extract information and/or as an intervention to effect change in the public knowledge, attitudes, and behavior/practice (KAB/P) were sought...

Safety of tenofovir disoproxil fumarate for pregnant women facing the coronavirus disease 2019 pandemic

2021

We assessed the teratogenicity of tenofovir, a human immunodeficiency virus (HIV) drug similar to remdesivir that is currently being evaluated for the treatment of coronavirus disease 2019 (COVID-19). Using US...

Current approaches to HIV vaccine development: A narrative review

2021

INTRODUCTION: The development of an effective vaccine to protect against HIV is a longstanding global health need complicated by challenges inherent to HIV biology and to the execution of vaccine...

HIV protease inhibitors and insulin sensitivity: A systematic review and meta-analysis of randomized controlled trials

2021

Background: Protease inhibitors (PIs) are believed to affect insulin sensitivity. We aimed to analyze the effect of PIs on insulin sensitivity and the onset of diabetes mellitus (DM) in patients with...

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