Category Archives: Prevention, Engagement and Care Cascade

CRISPR-edited stem cell transplantation for HIV-related gene modificationin vivo: A systematic review

2022

BACKGROUND: CRISPR is a novel genomic editing technology which can be useful for the treatment of immune diseases such as HIV. However, the application of CRISPR in stem cells for...

Comparative efficacy and safety of antifungal agents in the prophylaxis of oropharyngeal candidiasis among HIV-infected adults: A systematic review and network meta-analysis

2022

The objective of the study was to compare the efficacy and safety of antifungal agents used in the prevention of oropharyngeal candidiasis among HIV-infected adults. A systematic search was conducted...

Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: A systematic review and meta-analysis

2022

Background: There are 15·4 million children who are HIV-exposed and uninfected worldwide. Early child development crucially influences later academic and socioeconomic factors. However, the neurodevelopmental outcomes of HIV-exposed uninfected (HEU) children...

Efficacy of covid-19 vaccines in immunocompromised patients: Systematic review and meta-analysis

2022

Objective: To compare the efficacy of covid-19 vaccines between immunocompromised and immunocompetent people. Design: Systematic review and meta-analysis. Data sources: PubMed, Embase, Central Register of Controlled Trials, COVID-19 Open Research Dataset Challenge (CORD-19),...

Review of human papillomavirus (HPV) burden and HPV vaccination for gay, bisexual, and other men who have sex with men and transgender women in the United States

2022

Gay, bisexual, and other men who have sex with men (MSM) and transgender women, particularly those who are living with HIV, are disproportionately affected by human papillomavirus (HPV). For this...

Barriers and facilitators to acceptability of the female condom in low- and middle-income countries: A systematic review

2022

BACKGROUND: Sexually transmitted infections, including HIV, remain a significant public health challenge for low- and middle-income countries, and about 111 million unintended pregnancies occur in these countries annually. The female...

Queering poppers literature: A critical interpretive synthesis of health sciences research on alkyl nitrite use and Canadian policy

2022

BACKGROUND: Poppers (alkyl nitrites) are vasodilators used by many gay, bisexual, and other men who have sex with men (GBMSM) to relieve pain, enhance pleasure, and facilitate penetration during sex....

Integration of family planning into HIV services: A systematic review

2022

BACKGROUND: The unmet need for safe and effective contraception still remains high. In 2017, about 25% of women of childbearing age who wanted to avoid pregnancy in the developing world...

Integrative literature review of evidence-based guidelines on antiretroviral therapy adherence among adult persons living with HIV

2022

AIM: To summarize recommendations from available evidence-based guidelines that enhance, address or guide antiretroviral therapy adherence among adult persons living with human immunodeficiency virus. DESIGN: An integrative literature review approach....

Roles, barriers, and recommendations for community health workers providing community-based HIV care in sub-Saharan Africa: A review

2022

While the impact of Community Health Workers (CHWs) on home-based human immunodeficiency virus (HIV) care has been documented, barriers and recommendations have not been systematically reviewed. Following the reporting requirements...

National burden of intestinal parasitic infections and its determinants among people living with HIV/AIDS on anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis

2022

Objectives: The aim of this systematic review and meta-analysis is designed to assess the pooled prevalence and determine risk factors of intestinal parasitic infections among people living with HIV/AIDS on anti-retroviral...

Burden and associated factors of virological failure among people living with HIV in sub-Saharan Africa: A systematic review and meta-analysis

2022

United Nations program on HIV/AIDS 90-90-90 ambitious goal recommends 90% of people living with HIV and taking antiretroviral therapy should achieve viral suppression by 2020. However, virological failure is still...

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