Category Archives: Prevention, Engagement and Care Cascade

HIV patients retention and attrition in care and their determinants in Ethiopia: A systematic review and meta-analysis

2020

BACKGROUND: There is paucity of evidence on the magnitude of HIV patients’ retention and attrition in Ethiopia. Hence, the aim of this study was to determine the pooled magnitude of...

Pharmacokinetics of antiretroviral and tuberculosis drugs in children with HIV/TB co-infection: a systematic review

2020

INTRODUCTION: Management of concomitant use of ART and TB drugs is difficult because of the many drug-drug interactions (DDIs) between the medications. This systematic review provides an overview of the...

A cascade of interventions to promote adherence to antiretroviral therapy in African countries

2020

PURPOSE OF REVIEW: We reviewed interventions to improve uptake and adherence to antiretroviral therapy (ART) in African countries in the Treat All era. RECENT FINDINGS: ART initiation can be improved...

Sexually transmitted infections in pregnancy: A narrative review of the global research gaps, challenges, and opportunities

2020

BACKGROUND: Sexually transmitted infections (STI), such as chlamydial, gonorrheal, and trichomonal infection, are prevalent in pregnant women in many countries and are widely reported to be associated with increased risk...

Cognitive and educational interventions for orphans and vulnerable children affected by HIV/AIDS: A meta-analysis

2020

Orphans and vulnerable children affected by HIV/AIDS (HIV OVC) are at risk for cognitive difficulties and lack of access to education. Interventions addressing cognitive or educational outcomes for HIV OVC...

Mother-to-child HIV transmission and its correlates in India: Systematic review and meta-analysis

2020

BACKGROUND: In India, preventing mother-to-child transmission (PMTCT) of Human Immunodeficiency Virus (HIV) remains one of the foremost challenge in community health. Countrywide MTCT of HIV is estimated to be >ƒ_%10,000...

Is it time to RE-AIM? A systematic review of economic empowerment as HIV prevention intervention for adolescent girls and young women in sub-Saharan Africa using the RE-AIM framework

2020

BACKGROUND: Economic empowerment (EE) HIV prevention programs for adolescent girls and young women (AGYW) in sub-Saharan Africa are gaining traction as effective strategies to reduce HIV risk and vulnerabilities among...

Cervical cancer screening uptake and associated factors among HIV-positive women in Ethiopia: A systematic review and meta-analysis

2020

Background Cervical cancer is the leading cause of cancer deaths among women in developing countries. Since cervical cancer is a preventable disease, screening is an important control and prevention strategy,...

Human immunodeficiency virus prevention for people who use drugs: Overview of reviews and the ICOS of PICOS

2020

BACKGROUND: This article summarizes the results from systematic reviews of human immunodeficiency virus (HIV) prevention interventions for people who use drugs (PWUD). We performed an overview of reviews, meta-analysis, meta-epidemiology,...

Prevalence of transfusion transmissible infections in beta-thalassemia major patients in Pakistan: A systematic review

2020

Iý-thalassemia major (TM) is one of the most prevalent inherited hemoglobinopathies in Pakistan. It has one of the highest prevalence of transfusion-dependent TM patients globally, with an estimated greater than...

Neuropathy complication of antiretroviral therapy in HIV/AIDS patients

2020

OBJECTIVES: Significant pain from HIV-associated sensory neuropathy (HIV-SN) affects 40% of HIV-infected individuals treated with antiretroviral therapy (ART). The most salient symptom of the neuropathy is pain, which frequently is...

Exploring relative preferences for HIV service features using discrete choice experiments: A synthetic review

2020

PURPOSE OF REVIEW: Aligning HIV treatment services with patient preferences can promote long-term engagement. A rising number of studies solicit such preferences using discrete choice experiments, but have not been...

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