Category Archives: Prevention, Engagement and Care Cascade
Systematic review of spontaneous reports of myocarditis and pericarditis in transplant recipients and immunocompromised patients following COVID-19 mRNA vaccination
OBJECTIVES: To determine whether spontaneous reporting rates of myocarditis and pericarditis differed in immunocompromised patients compared with the whole population overall, and in terms of demographics, vaccine dose and time-to-onset....
Treatments for AIDS/HIV-related Kaposi sarcoma: A systematic review of the literature
BACKGROUND: Treatment guidelines are not well established in AIDS-related Kaposi sarcoma (KS). OBJECTIVE: We aim to review the evidence on efficacy of treatments for AIDS-related Kaposi sarcoma. METHODS: We searched...
Exploring barriers to antiretroviral therapy adherence among pregnant women: A scoping literature review
BACKGROUND: Antiretroviral therapy (ART) is one of the most effective ways of preventing HIV-related maternal mortality. However, the rates of retention in care and long-term adherence remain extremely low. OBJECTIVE:...
A systematic review of factors critical for HIV health literacy, ART adherence and retention in care in the U.S. for racial and ethnic minorities
Despite advances in antiretroviral treatment (ART), the HIV epidemic persists in the United States (U.S.), with inadequate adherence to treatment and care a major barrier to ending the epidemic. Health...
Weight changes with integrase strand transfer inhibitor therapy in the management of HIV infection: A systematic review
OBJECTIVE: To describe weight changes with integrase strand transfer inhibitor (INSTI) therapy. DATA SOURCES: A literature search was performed (through December 15, 2021) using the PubMed and CINAHL databases using...
A review of internet-based testing services for HIV and sexually transmitted infections (STIs)
Key take-home messages The integration of digital technologies into HIV and STI testing is becoming more prevalent, and appears to influence testing behaviours. Three models offering online HIV/STI testing that...
Risk of immune reconstitution inflammatory syndrome with integrase inhibitors versus other classes of antiretrovirals: A systematic review and meta-analysis of randomised trials
Background: Integrase strand transfer inhibitors (InSTIs) decrease HIV plasma viral load faster than other antiretroviral classes. More rapid viral load decline has been associated with higher risk of immune reconstitution inflammatory...
Public health implications of adapting HIV pre-exposure prophylaxis programs for virtual service delivery in the context of the COVID-19 pandemic: A systematic review
BACKGROUND: The novel coronavirus disease-19 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) threatens to disrupt global progress towards HIV epidemic control. Opportunities exist to leverage ongoing...
Detection of HIV virologic failure and switch to second-line therapy: A systematic review and meta-analysis of data from sub-Saharan Africa
BACKGROUND: The late recognition of virologic failure (VF) places persons with HIV in Sub-Saharan Africa at risk for HIV transmission, disease progression, and death. We conducted a systematic review and...
Treatment failure and its associated factors among children receiving highly active antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
OBJECTIVES: Over the last decades, large number of children living with human immunodeficiency virus (HIV) have been successfully enrolled in care and initiated treatment. However, treatment failure is still a...
