Category Archives: Prevention, Engagement and Care Cascade

Acceptability of HIV pre-exposure prophylaxis in China: A systematic review and meta-analysis

2022

Using pre-exposure prophylaxis (PrEP) for the prevention of HIV infection is a popular, contemporary research topic. We retrieved PubMed, Web of Science, MEDLINE, Wanfang, CNKI, and Sinomed databases, and related...

Cost-effectiveness of HIV retention and re-engagement interventions in high-income countries: A systematic literature review

2022

Engagement in lifelong HIV care is critical for both patient and public health, yet there are limited resources to invest in improving HIV outcomes. We systematically reviewed evidence on the...

Identifying and managing infectious disease syndemics in patients with HIV

2020

PURPOSE OF REVIEW: We will present recent articles focusing on HIV synergistic interactions with other sexually transmitted infections, tuberculosis, and hepatitis, as well as recent advances in the study of...

Characterizing the role of intersecting stigmas and sustained inequities in driving HIV syndemics across low-to-middle-income settings

2020

PURPOSE OF REVIEW: In 2020, key populations around the world still have disproportionate risks for HIV acquisition and experiencing HIV-related syndemics. This review presents current data around HIV-related syndemics among...

Shared immunotherapeutic approaches in HIV and hepatitis B virus: Combine and conquer

2020

PURPOSE OF REVIEW: The aim of this study was to identify similarities, differences and lessons to be shared from recent progress in HIV and hepatitis B virus (HBV) immunotherapeutic approaches....

Challenges and opportunities for hepatitis B cure in the setting of HIV–Hepatitis B virus co-infection

2020

PURPOSE OF REVIEW: To examine issues specific to HIV–HBV co-infection that are relevant to the search for and achieving hepatitis B cure in this the setting RECENT FINDINGS: In HIV–HBV...

Enhancing care for people living with HIV: Current and future monitoring approaches

2021

INTRODUCTION: Antiretroviral therapy (ART) is the most significant advance in the medical management of HIV-1 infection. Given the fact that HIV cannot be eradicated from the body, ART has to...

Adolescents and young adults with early acquired HIV infection in the United States: Unique challenges in treatment and secondary prevention

2021

INTRODUCTION: Worldwide, children who acquired human immunodeficiency virus (HIV) at an early age, either perinatally or through blood transfusion, are reaching adolescence and adulthood due to successful antiretroviral treatment (ART)....

Efavirenz versus protease inhibitors in patients with HIV: A systematic review and meta-analysis

2021

Efavirenz- and protease inhibitor (PI)-based regimens remain viable options across the globe. We conducted a meta-analysis to compare the effectiveness of efavirenz-based regimens relative to PI-based regimens. EMBASE, PubMed, Cochrane,...

Low inducibility of latent human immunodeficiency virus type 1 proviruses as a major barrier to cure

2021

The latent reservoir for human immunodeficiency virus type 1 (HIV-1) in resting CD4+ T cells is a major barrier to cure. The dimensions of the reservoir problem can be defined...

Evidence and gaps in the literature on HIV/STI prevention interventions targeting migrants in receiving countries: A scoping review

2021

BACKGROUND: Evidence suggests that migration increases vulnerability to human immunodeficiency virus (HIV) and other sexually transmitted infections (STI). However, there is limited knowledge about what has been done or needs...

Recommendations for increasing physician provision of pre-exposure prophylaxis: Implications for medical student training

2021

There is growing evidence that pre-exposure prophylaxis (PrEP) prevents HIV acquisition. However, in the United States, approximately only 4% of people who could benefit from PrEP are currently receiving it,...

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