Category Archives: Prevention, Engagement and Care Cascade
Burden and associated factors of virological failure among people living with HIV in sub-Saharan Africa: A systematic review and meta-analysis
United Nations program on HIV/AIDS 90-90-90 ambitious goal recommends 90% of people living with HIV and taking antiretroviral therapy should achieve viral suppression by 2020. However, virological failure is still...
Factors associated with viral suppression among cisgender women living with human immunodeficiency virus in the United States: An integrative review
Introduction: Women account for 23% of new human immunodeficiency virus diagnoses in the United States, yet remain understudied. Adherence to antiretroviral therapy and consequent viral suppression are keys to preventing human...
eHealth interventions to address HIV and other sexually transmitted infections, sexual risk behavior, substance use, and mental ill-health in men who have sex with men: Systematic review and meta-analysis
Background: Men who have sex with men experience disproportionately high levels of HIV and other sexually transmitted infections (STIs), sexual risk behavior, substance use, and mental ill-health. These experiences are interrelated,...
Effectiveness and safety analysis of PIs/r based dual therapy in treatment-naïve, HIV/AIDS patients: A network meta analysis of randomized controlled trials
Background: Dual anti-retroviral therapy is the main proven valuable intervention type for treating naïve HIV/AIDS. Currently, no high-quality evidence is available regarding the best dual schemes. Objectives: The aim of this study is...
Interventions to improve treatment outcomes among adolescents on antiretroviral therapy with unsuppressed viral Loads: A systematic review
Adolescents living with HIV (ALHIV) face unique developmental challenges that increase the risk of unsuppressed viral loads. Current reviews present a need for proven interventions to improve viral suppression among...
Queering poppers literature: A critical interpretive synthesis of health sciences research on alkyl nitrite use and Canadian policy
BACKGROUND: Poppers (alkyl nitrites) are vasodilators used by many gay, bisexual, and other men who have sex with men (GBMSM) to relieve pain, enhance pleasure, and facilitate penetration during sex....
A systematic review of the effects of intimate partner violence on HIV-positive pregnant women in sub-Saharan Africa
BACKGROUND: Intimate partner violence (IPV) affects more than one in three women in sub-Saharan Africa (SSA). It is associated with both pregnancy and HIV, adversely affecting women in this region....
Risky sexual practice and associated factors among people living with HIV/AIDS receiving antiretroviral therapy in Ethiopia: Systematic review and meta-analysis
BACKGROUND: The risky sexual behavior of people living with HIV/AIDS (PLWHA) may impose a risk of transmitting the disease to their partners and increase Human Immunodeficiency Virus (HIV) co-infection. This...
The role of innate immunity in natural elite controllers of HIV-1 infection
The natural process of human immunodeficiency virus type 1(HIV-1) infection is characterized by high viral load, immune cell exhaustion, and immunodeficiency, which eventually leads to the stage of acquired immunodeficiency...
Use of quality-of-life instruments for people living with HIV: A global systematic review and meta-analysis
Introduction: Due to the effectiveness of combined antiretroviral therapy and its growing availability worldwide, most people living with HIV (PLHIV) have a near-normal life expectancy. However, PLHIV continue to face various...
Pre-exposure prophylaxis interventions among Black sexual minority men: A systematic literature review
BACKGROUND: Interventions to promote HIV pre-exposure prophylaxis (PrEP) among Black sexual minority men (BSMM) are especially important, given the disproportionate HIV incidence and relatively low uptake of PrEP among BSMM....
Pharmacokinetic outcomes of the interactions of antiretroviral agents with food and supplements: A systematic review and meta-analysis
Because pharmacokinetic changes in antiretroviral drugs (ARV), due to their concurrent administration with food or nutritional products, have become a clinical challenge, it is necessary to monitor the therapeutic efficacy...
