Category Archives: Prevention, Engagement and Care Cascade

A systematic review and network meta-analyses to assess the effectiveness of human immunodeficiency virus (HIV) self-testing distribution strategies

2021

BACKGROUND: We conducted a systematic review and network meta-analysis to identify which human immunodeficiency virus (HIV) self-testing (HIVST) distribution strategies are most effective. METHODS: We abstracted data from randomized controlled...

Improving retention in antenatal and postnatal care: A systematic review of evidence to inform strategies for adolescents and young women living with HIV

2021

INTRODUCTION: Young pregnant and postpartum women living with HIV (WLHIV) are at high risk of poor outcomes in prevention of mother-to-child transmission services. The aim of this systematic review was...

A systematic review and meta-analysis of studies evaluating the effect of medication treatment for opioid use disorder on infectious disease outcomes

2021

The opioid epidemic has fueled infectious disease epidemics. We determined the impact of medications for opioid use disorder (MOUD) on treatment outcomes of opioid use disorder (OUD)-associated infectious diseases: antiretroviral...

Barriers and facilitators affecting the HIV care cascade for migrant people living with HIV in Organization for Economic Co-Operation and Development Countries: A systematic mixed studies review

2021

Migrants in countries affiliated with the Organization for Economic Co-operation and Development (OECD) have a higher risk of acquiring HIV, experience delayed HIV diagnosis, and have variable levels of engagement...

Law, criminalisation and HIV in the world: Have countries that criminalise achieved more or less successful pandemic response?

2021

How do choices in criminal law and rights protections affect disease-fighting efforts? This long-standing question facing governments around the world is acute in the context of pandemics like HIV and...

Psychosocial interventions for improving engagement in care and health and behavioural outcomes for adolescents and young people living with HIV: A systematic review and meta-analysis

2021

INTRODUCTION: Adolescents and young people comprise a growing proportion of new HIV infections globally, yet current approaches do not effectively engage this group, and adolescent HIV-related outcomes are the poorest...

The manifesto of pharmacoenosis: Merging HIV pharmacology into pathocoenosis and syndemics in developing countries

2021

Pathocoenosis and syndemics theories have emerged in the last decades meeting the frequent need of better understanding interconnections and reciprocal influences that coexistent communicable and non-communicable diseases play in a...

Complex solutions for a complex problem: A meta-analysis of the efficacy of multiple-behavior interventions on change in outcomes related to HIV

2021

OBJECTIVE: The purpose of this meta-analysis was to examine the success of multiple-behavior interventions and to identify whether the efficacy of such programs depends on the number of recommendations prescribed...

Bioactive compounds as potential agents for sexually transmitted diseases management: A review to explore molecular mechanisms of action

2021

Sexually transmitted diseases (STDs) are produced by pathogens like bacteria, fungi, parasites, and viruses, and may generate severe health problems such as cancer, ulcers, and even problems in the newborn....

Effectiveness of eHealth interventions for HIV prevention and management in sub-Saharan Africa: Systematic review and meta-analyses

2021

HIV is still the leading cause of death in Sub-Saharan Africa (SSA), despite medical advances. eHealth interventions are effective for HIV prevention and management, but it is unclear whether this...

HIV treatment with the two-drug regimen dolutegravir plus lamivudine in real-world clinical practice: A systematic literature review

2021

The two-drug regimen dolutegravir plus lamivudine demonstrated durable efficacy for up to 3 years in phase III studies and a high barrier to resistance in treatment-naive and virologically suppressed people...

Sex differences in HIV testing among older adults in sub-Saharan Africa: A systematic review

2021

BACKGROUND: Despite being sexually active and engaging in risky sexual behaviours similar to young adults, older adults (50 years or older) are less likely to receive HIV testing, and disaggregated...

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