Category Archives: Prevention, Engagement and Care Cascade
Effects of probiotics on diarrhea and CD4 cell count in people living with HIV: A systematic review and meta-analysis
Gastrointestinal probiotics play an important role in maintaining intestinal bacteria homeostasis. They might benefit people with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), which remains a global health challenge. However, there...
Assessing proviral competence: Current approaches to evaluate HIV-1 persistence
PURPOSE OF REVIEW: Despite decades of suppressive antiretroviral therapy (ART), HIV-1 reservoirs persist and fuel viral rebound if therapy is interrupted. The persistence of viral reservoirs in infected individuals is...
Increased risk of vitamin D deficiency among HIV-infected individuals: A systematic review and meta-analysis
Background: Human immunodeficiency virus (HIV) infection is a heavy burden worldwide. Observational studies have reported a high prevalence of vitamin D deficiency (VDD) among people living with HIV (PLWH). However,...
Dual contraceptive use and factor associated with people living with HIV/AIDS: A systematic review and meta-analysis
INTRODUCTION: A dual contraceptive method is the usage of any modern contraceptive method with male or female condoms which could lower sexually transmitted diseases and unwanted pregnancy. Ethiopian standard utilization...
A systematic review and network meta-analyses to assess the effectiveness of human immunodeficiency virus (HIV) self-testing distribution strategies
BACKGROUND: We conducted a systematic review and network meta-analysis to identify which human immunodeficiency virus (HIV) self-testing (HIVST) distribution strategies are most effective. METHODS: We abstracted data from randomized controlled...
Improving retention in antenatal and postnatal care: A systematic review of evidence to inform strategies for adolescents and young women living with HIV
INTRODUCTION: Young pregnant and postpartum women living with HIV (WLHIV) are at high risk of poor outcomes in prevention of mother-to-child transmission services. The aim of this systematic review was...
Video-based teleconsultations in pharmaceutical care – A systematic review
BACKGROUND: In recent years, telemedicine has gained increasing importance in the delivery of pharmaceutical care. The use of video technologies for remote communication between different parties offers the potential to...
Patient-reported outcomes in HIV clinical trials evaluating antiretroviral treatment: A systematic review
We aimed to assess patterns of patient-reported outcomes (PRO) instruments’ utilization in HIV clinical trials in relation to antiretroviral therapy (ART). PubMed/MEDLINE, Scopus, and EMBASE were searched using the terms...
Patients’ preferences for antiretroviral therapy service provision: A systematic review
BACKGROUND: Achieving global targets of adherence to treatment, retention in care, and treatment success remains a challenge. Health system investment to make antiretroviral therapy services more responsive to patients’ needs...
Strategies to reengage patients lost to follow up in HIV care in high income countries, a scoping review
BACKGROUND: Despite remarkable achievements in antiretroviral therapy (ART), losses to follow-up (LTFU) might prevent the long-term success of HIV treatment and might delay the achievement of the 90-90-90 objectives. This...
