Category Archives: Prevention, Engagement and Care Cascade
Drug-drug interactions in people living with HIV at risk of hepatic and renal impairment: Current status and future perspectives
Despite the advancement of antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV), drug-drug interactions (DDIs) remain a relevant clinical issue for people living with HIV receiving ART....
Strategies to improve HIV care outcomes for people with HIV who are out of care: a meta-analysis
Objective: The aim of this study was to evaluate the effectiveness of five intervention strategies: patient navigation, appointment help/alerts, psychosocial support, transportation/appointment accompaniment, and data-to-care on HIV care outcomes among persons...
The effectiveness and characteristics of mHealth interventions to increase adolescent’s use of sexual and reproductive health services in sub-Saharan Africa: A systematic review
BACKGROUND: mHealth innovations have been proposed as an effective solution to improving adolescent access to and use of Sexual and Reproductive Health (SRH) services; particularly in regions with deeply entrenched...
Cost-effectiveness of HIV retention and re-engagement interventions in high-income countries: A systematic literature review
Engagement in lifelong HIV care is critical for both patient and public health, yet there are limited resources to invest in improving HIV outcomes. We systematically reviewed evidence on the...
Safety of antiretroviral therapy in the treatment of HIV/AIDS in children: Systematic review and meta-analysis
The safety of using different antiretroviral therapies (ART) in pediatric HIV/AIDS patients is not well-established. Therefore, this study aimed to assess the safety of ART in children. A systematic review...
SARS-CoV-2 infection and coronavirus disease 2019 severity in persons with HIV on antiretroviral treatment
The relative susceptibility of people with HIV (PWH) to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is debated. Numerous studies have been published with apparently contradictory findings, but comparisons...
Where are the pregnant and breastfeeding women in new pre-exposure prophylaxis trials? The imperative to overcome the evidence gap
Pregnant and breastfeeding populations are at substantial risk of acquiring HIV in some settings, yet are underrepresented in clinical trials of new pre-exposure prophylaxis (PrEP) agents. Several PrEP formulations are...
A systematic review of linkage-to-care and antiretroviral initiation implementation strategies in low- and middle-income countries across sub-Saharan Africa
Linkage to care (LTC) and initiation of antiretroviral therapy (ART) are key components in the longitudinal care cascade for people living with HIV. Many strategies to optimize these stages of...
Risk of vertical transmission of chronic viral infections after invasive prenatal procedures
OBJECTIVES: Invasive prenatal procedures including amniocentesis, chorionic villus sampling (CVS) can be prenatally indicated for diagnostic purposes. Chronic viral infections with Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), hepatitis...
Acceptability of HIV pre-exposure prophylaxis in China: A systematic review and meta-analysis
Using pre-exposure prophylaxis (PrEP) for the prevention of HIV infection is a popular, contemporary research topic. We retrieved PubMed, Web of Science, MEDLINE, Wanfang, CNKI, and Sinomed databases, and related...
