Category Archives: Prevention, Engagement and Care Cascade

Contraception values and preferences of people living with HIV: A systematic review

2021

OBJECTIVE: Attention to the contraception values and preferences of those living with HIV is essential to meeting their reproductive rights and health needs. We systematically reviewed the literature on contraception...

Validated HIV knowledge scales for use with adults and adolescents: A systematic review

2021

HIV knowledge—the information a person possesses about HIV—is essential for the prevention and management of HIV. Therefore, the accurate measurement of HIV knowledge is important for both science and practice....

Storytelling as a research tool used to explore insights and as an intervention in public health: A systematic narrative review

2021

Objectives: Studies of storytelling (ST) used as a research tool to extract information and/or as an intervention to effect change in the public knowledge, attitudes, and behavior/practice (KAB/P) were sought...

Safety of tenofovir disoproxil fumarate for pregnant women facing the coronavirus disease 2019 pandemic

2021

We assessed the teratogenicity of tenofovir, a human immunodeficiency virus (HIV) drug similar to remdesivir that is currently being evaluated for the treatment of coronavirus disease 2019 (COVID-19). Using US...

Current approaches to HIV vaccine development: A narrative review

2021

INTRODUCTION: The development of an effective vaccine to protect against HIV is a longstanding global health need complicated by challenges inherent to HIV biology and to the execution of vaccine...

HIV protease inhibitors and insulin sensitivity: A systematic review and meta-analysis of randomized controlled trials

2021

Background: Protease inhibitors (PIs) are believed to affect insulin sensitivity. We aimed to analyze the effect of PIs on insulin sensitivity and the onset of diabetes mellitus (DM) in patients with...

Pre-exposure prophylaxis uptake, adherence, and persistence: A narrative review of interventions in the U.S

2021

Since 2012, HIV pre-exposure prophylaxis (PrEP) has been available to prevent HIV transmission; yet, uptake, adherence, and persistence to PrEP have been suboptimal. This narrative review examines the latest interventions...

A scoping review investigating relationships between depression, anxiety, and the PrEP care continuum in the United States

2021

Men who have sex with men and transgender women in the United States are at increased risk for HIV and may benefit from pre-exposure prophylaxis (PrEP), a once-a-day pill to...

Mother-to-child HIV-2 transmission: Comparison with HIV-1 and evaluation of factors influencing the rate of transmission. A systematic review

2021

A review and collection of data on HIV-2 mother-to-child transmission (MTCT) is absent in the literature. This systematic review and meta-analysis aims to provide a pooled estimate of the rate...

Patient perspectives on integrated healthcare for HIV, hypertension and type 2 diabetes: A scoping review

2021

INTRODUCTION: Antiretroviral therapy has reduced mortality and led to longer life expectancy in people living with HIV. These patients are now at an increased risk of non-communicable diseases (NCDs). Integration...

Barriers to and enablers of uptake of antiretroviral therapy in integrated HIV and tuberculosis treatment programmes in sub-Saharan Africa: A systematic review and meta-analysis

2021

Introduction Programmes that merge management of Human Immunodeficiency Virus (HIV) and tuberculosis (TB) aim to improve HIV/TB co-infected patients’ access to comprehensive treatment. However, several reports from sub-Saharan Africa (SSA)...

Psychosocial interventions to promote undetectable HIV viral loads: A systematic review of randomized clinical trials

2021

Suppressing HIV viral loads to undetectable levels is essential for ending the HIV/AIDS epidemic. We evaluated randomized controlled trials aimed to increase antiretroviral medication adherence and promote undetectable viral loads...

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