Category Archives: Prevention, Engagement and Care Cascade

Barriers and facilitators affecting the HIV care cascade for migrant people living with HIV in Organization for Economic Co-Operation and Development Countries: A systematic mixed studies review

2021

Migrants in countries affiliated with the Organization for Economic Co-operation and Development (OECD) have a higher risk of acquiring HIV, experience delayed HIV diagnosis, and have variable levels of engagement...

Law, criminalisation and HIV in the world: Have countries that criminalise achieved more or less successful pandemic response?

2021

How do choices in criminal law and rights protections affect disease-fighting efforts? This long-standing question facing governments around the world is acute in the context of pandemics like HIV and...

Psychosocial interventions for improving engagement in care and health and behavioural outcomes for adolescents and young people living with HIV: A systematic review and meta-analysis

2021

INTRODUCTION: Adolescents and young people comprise a growing proportion of new HIV infections globally, yet current approaches do not effectively engage this group, and adolescent HIV-related outcomes are the poorest...

The manifesto of pharmacoenosis: Merging HIV pharmacology into pathocoenosis and syndemics in developing countries

2021

Pathocoenosis and syndemics theories have emerged in the last decades meeting the frequent need of better understanding interconnections and reciprocal influences that coexistent communicable and non-communicable diseases play in a...

Nutrition in HIV-infected infants and children: Current knowledge, existing challenges, and new dietary management opportunities

2021

HIV infection and undernutrition remain significant public health concerns for infants and children. In infants and children under these conditions, undernutrition is one of the leading causes of death. Proper...

Effect of pharmacist care on clinical outcomes among people living with HIV/AIDS: A systematic review and meta-analysis

2021

BACKGROUND: Pharmacists play a significant role in the multidisciplinary care of people living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) (PLWHA). However, there is less evidence to clarify the...

Effects of probiotics on diarrhea and CD4 cell count in people living with HIV: A systematic review and meta-analysis

2021

Gastrointestinal probiotics play an important role in maintaining intestinal bacteria homeostasis. They might benefit people with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), which remains a global health challenge. However, there...

Eliminating HIV reservoirs for a cure: The issue is in the tissue

2021

PURPOSE OF REVIEW: Advances in antiretroviral therapy have saved numerous lives, converting a diagnosis with human immunodeficiency virus 1 (HIV-1) from a death sentence into the possibility for a (nearly)...

Assessing proviral competence: Current approaches to evaluate HIV-1 persistence

2021

PURPOSE OF REVIEW: Despite decades of suppressive antiretroviral therapy (ART), HIV-1 reservoirs persist and fuel viral rebound if therapy is interrupted. The persistence of viral reservoirs in infected individuals is...

A systematic review of the engagement with social media-delivered interventions for improving health outcomes among sexual and gender minorities

2021

BACKGROUND: Sexual and gender minority (SGM) persons face a number of physical and mental health disparities closely linked to discrimination, social stigma, and victimization. Despite the acceptability and increasing number...

Prescribing intranasal steroids in HIV-positive patients: Systematic review of the literature

2021

BACKGROUND: There are significant drug-drug interactions between human immunodeficiency virus antiretroviral therapy and intranasal steroids, leading to high serum concentrations of iatrogenic steroids and subsequently Cushing’s syndrome. METHOD: All articles...

Considerations for successful therapeutic immunization in HIV cure

2021

PURPOSE OF REVIEW: In this special issue on human immunodeficiency (HIV) cure, we review the role of therapeutic immunization in strategies aimed to eliminate HIV-infected cells and/or mediate sustained control...

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