Category Archives: Prevention, Engagement and Care Cascade
The effects of antidepressant medications on antiretroviral treatment adherence in HIV-positive individuals with depression
Background Extant literature has identified Major Depressive Disorder (MDD) as a comorbid disorder in individuals with seropositive human immunodeficiency disorder (HIV), and this may affect HIV-treatment efficacy. However, there is...
Decade of research into the acceptability of interventions aimed at improving adolescent and youth health and social outcomes in Africa: A systematic review and evidence map
OBJECTIVE: Interventions aimed at improving adolescent health and social outcomes are more likely to be successful if the young people they target find them acceptable. However, no standard definitions or...
Reproductive justice in the time of COVID-19: A systematic review of the indirect impacts of COVID-19 on sexual and reproductive health
OBJECTIVE: Despite gendered dimensions of COVID-19 becoming increasingly apparent, the impact of COVID-19 and other respiratory epidemics on women and girls’ sexual and reproductive health (SRH) have yet to be...
Understanding the epidemiological HIV risk factors and underlying risk context for youth residing in or originating from the Middle East and North Africa (MENA) region: A scoping review of the literature
INTRODUCTION: HIV is the second leading cause of death among young people globally, and adolescents are the only group where HIV mortality is not declining. Middle East and North Africa...
Microbiota-meditated immunity abnormalities facilitate hepatitis B virus co-infection in people living with HIV: A review
Hepatitis B virus (HBV) co-infection is fairly common in people living with HIV (PLWH) and affects millions of people worldwide. Identical transmission routes and HIV-induced immune suppression have been assumed...
Drug-drug interactions in people living with HIV at risk of hepatic and renal impairment: Current status and future perspectives
Despite the advancement of antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV), drug-drug interactions (DDIs) remain a relevant clinical issue for people living with HIV receiving ART....
The effectiveness and characteristics of mHealth interventions to increase adolescent’s use of sexual and reproductive health services in sub-Saharan Africa: A systematic review
BACKGROUND: mHealth innovations have been proposed as an effective solution to improving adolescent access to and use of Sexual and Reproductive Health (SRH) services; particularly in regions with deeply entrenched...
Community-based ART service delivery for key populations in sub-Saharan Africa: Scoping review of outcomes along the continuum of HIV care
HIV positive key population (KP) often face health system and social barriers to HIV care. KP include sex workers, men who have sex with men, persons who inject drugs, transgender...
The cost-effectiveness of HIV/STI prevention in high-income countries with concentrated epidemic settings: A scoping review
The purpose of this scoping review is to establish the state of the art on economic evaluations in the field of HIV/STI prevention in high-income countries with concentrated epidemic settings...
Risk of HIV acquisition among high-risk heterosexuals with nonviral sexually transmitted infections: A systematic review and meta-analysis
BACKGROUND: Nonviral sexually transmitted infections (STIs) increase risk of sexually-acquired HIV infection. Updated risk estimates carefully scrutinizing temporality bias of studies are needed. METHODS: We conducted a systematic review (PROSPERO...
