Category Archives: Prevention, Engagement and Care Cascade

The association between different levels of suppressed viral load and the risk of sexual transmission of HIV among serodiscordant couples on antiretroviral therapy: A systematic review

2025

The risk of sexual transmission of HIV in serodiscordant couples when the partner living with HIV (PLHIV) uses antiretroviral therapy (ART) and maintains a suppressed viral load (VL) (< 200...

Prevalence of fungemia in people with HIV: A systematic review and meta-analysis

2026

Prior to the introduction of antiretroviral therapy (ART), people with HIV (PWH) had high risk of fungemia. No systematic review has assessed the prevalence of fungemia in PWH after the...

Risk prediction models for targeted testing of HIV, hepatitis B and hepatitis C: A systematic review and meta-analysis

2025

Background Diagnosing human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) infections in general population settings is challenging. We conducted a systematic review and meta-analysis of...

Pregnancy and neonatal outcomes of HIV infection in pregnant women in Iran: A systematic review and meta-analysis

2025

Background HIV infection is a major public health concern among pregnant women globally. Beyond the risk of mother-to-child transmission, it can lead to serious complications and negative pregnancy and neonatal...

Body image and its associated factors among people living with HIV: A scoping review and implications for integrated care

2025

People living with HIV (PLWH) face unique biopsychosocial challenges due to both infection and antiretroviral therapy (ART), one of which is body image disruption. This study comprehensively reviewed relevant studies...

Factors influencing antiretroviral therapy adherence among youth living with HIV: A systematic review and meta-analysis

2025

Background Adherence to antiretroviral therapy (ART) is vital for controlling the viral load and disease progression in people living with HIV. Previous reviews on ART adherence among youths living with...

Association between HIV infection and type 2 diabetes mellitus: Global incidence, prevalence, and risk factors—A systematic review and meta-analysis

2025

Introduction People living with HIV (PLHIV) are at an increased risk of type 2 diabetes mellitus (T2DM) due to aging, lifestyle, and antiretroviral therapy-related factors. This systematic review and meta-analysis...

Contextual and culturally adapted interventions to improve HIV outcomes: A scoping review

2025

BACKGROUND: Antiretroviral therapy is widely available, yet structural, social, and cultural barriers still limit human immunodeficiency virus prevention and care. Prevention tools such as consistent condom use and pre-exposure prophylaxis...

Promoting healthy aging through mindfulness and yoga: A systematic review of interventions for people living with HIV who use drugs or who have a history of substance use

2025

Advances in HIV care and broader access to antiretroviral therapy (ART) have extended life expectancy for people living with HIV, yet aging-related health concerns, especially among those who use substances,...

Viral load suppression after enhanced adherence counseling among HIV patients on antiretroviral therapy (2019–2024): A systematic review and meta-analysis in East Africa

2025

Introduction Viral load suppression is essential for reducing human immunodeficiency virus (HIV) related morbidity and mortality. To eliminate the HIV epidemic and enhance adherence to antiretroviral therapy (ART) globally, the...

The effect of Chinese medicine therapeutics on HIV/AIDS: A systematic review and network meta-analysis

2025

Background Although antiretroviral therapy (ART) effectively suppresses HIV, incomplete immune reconstitution affects 20%–30% of adherent patients. Chinese Medicine (CM) demonstrates potential as a complementary therapy for human immunodeficiency virus (HIV)/acquired...

Influences of gender-based stigma on HIV prevention and care among older women: A scoping review

2025

Older women living with HIV are uniquely situated at multiple marginalized intersections because of their gender, age, and HIV status. However, research into how gender-based stigma (GBS) affects HIV prevention...

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