Category Archives: Prevention, Engagement and Care Cascade

Incidence of loss to follow-up among East African adults on antiretroviral therapy: A systematic review and meta-analysis

2025

Background Individuals with human immunodeficiency virus receive antiretroviral treatment regardless of their clinical stage or CD4 count. While the “Universal Test and Treat” approach offers benefits, loss to follow-up remains...

An integrative review of PrEP promotion strategies at historically Black colleges and universities to reduce HIV disparities

2025

PURPOSE OF REVIEW: We searched PubMed, CINAHL Plus, Embase, Scopus, Web of Science, and ERIC to identify peer-reviewed studies published between 2015 and 2025 that discussed PrEP at HBCUs. We...

Pre-exposure prophylaxis care engagement among men who have sex with men in the United States during the COVID-19 pandemic: A scoping review

2025

The COVID-19 pandemic substantially impacted the pre-exposure prophylaxis (PrEP) care continuum among men who have sex with men (MSM). While PrEP use during the pandemic has been studied, regional differences...

Integration models for delivering COVID-19 vaccines through HIV services in low-and middle-income countries: A scoping review

2025

BACKGROUND: The Coronavirus Disease 2019 (COVID-19) remains a major global public health issue. People living with HIV (PLHIV) are among the vulnerable groups facing a higher risk of severe outcomes....

HIV pre-exposure prophylaxis among people with criminal justice involvement in the United States: A systematic review

2025

People with criminal justice involvement (PCJI) face a heightened risk of HIV yet remain underserved by prevention strategies such as pre-exposure prophylaxis (PrEP). This systematic review synthesizes current evidence on...

Burden and challenges of managing hypertension in people living with human immunodeficiency virus (HIV) infection in sub-Saharan African: A mixed systematic review and meta-analysis

2025

Objectives Poor hypertension prevention among people living with HIV (PLHIV) in sub-Saharan Africa may undermine progress in HIV prevention achieved within this population. This review synthesizes data on the prevalence,...

The pathological link between elevated markers of inflammation, endothelial activation, and cardiovascular diseases in people living with HIV on combination antiretroviral therapy: A systematic review

2025

Introduction Despite administering combination antiretroviral therapy (cART), people living with the human immunodeficiency virus (PLWH) have been identified to be at an elevated risk of cardiovascular diseases (CVDs). Notably, inflammation...

Investigating the influence of provider communication and language reframing on HIV pre-exposure prophylaxis (PrEP) engagement with Black African and Caribbean women: A systematic review

2025

Patient-provider engagement with HIV pre-exposure prophylaxis (PrEP) continues to exhibit significant disparities, particularly among Black African and Caribbean (BAC) women. In the United Kingdom, cisgender women accounted for one-third of...

Global prevalence of HIV and Mycobacterium tuberculosis co-infection: A systematic review and meta-analysis of 371 included articles

2025

OBJECTIVES: Tuberculosis and Human Immunodeficiency Virus (HIV) are two diseases that have imposed the heaviest burden globally. This study aims to determine the global prevalence of Mycobacterium tuberculosis and HIV...

Lessons from the field: A systematic review of global and continental prevalence and challenges of people living with HIV (COVID-19)

2025

COVID-19, caused by SARS-CoV-2, accounts for 186 million infections and more than 4 million deaths globally. This systematic review concentrates on the epidemiological profiling of HIV/AIDS, along with the unique...

Factors influencing antiretroviral therapy adherence among youth living with HIV: A systematic review and meta-analysis

2025

Background Adherence to antiretroviral therapy (ART) is vital for controlling the viral load and disease progression in people living with HIV. Previous reviews on ART adherence among youths living with...

Association between HIV infection and type 2 diabetes mellitus: Global incidence, prevalence, and risk factors—A systematic review and meta-analysis

2025

Introduction People living with HIV (PLHIV) are at an increased risk of type 2 diabetes mellitus (T2DM) due to aging, lifestyle, and antiretroviral therapy-related factors. This systematic review and meta-analysis...

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