Category Archives: Prevention, Engagement and Care Cascade

The prevalence of thrombocytopenia and leucopenia among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis

2021

INTRODUCTION: Thrombocytopenia and leucopenia are frequently encountered hematological disorders among people living with HIV/AIDS. This systematic review and meta-analysis were aimed to indicate the national prevalence of thrombocytopenia and leucopenia...

The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer

2021

Cervical cancer is a public health problem and has devastating effects in low-to-middle-income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by the human papillomavirus (HPV) is the...

HIV continuum of care: Expanding scope beyond a cross-sectional view to include time analysis: A systematic review

2021

INTRODUCTION: The continuum of care (CoC) model has been used to describe the main pillars of HIV care. This study aims to systematically review methods and elucidate gaps in the...

Same-day antiretroviral therapy initiation for people living with HIV who have tuberculosis symptoms: A systematic review

2021

Objectives Tuberculosis symptoms are very common among people living with HIV (PLHIV) initiating antiretroviral therapy (ART), are not specific for tuberculosis disease and may result in delayed ART start. The...

Association between adherence to antiretroviral therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis

2021

BACKGROUND: According to the World Health Organization, optimal adherence to Antiretroviral Therapy (ART) improves quality of life. Patients who use ART have varying characteristics in terms of where they live....

HIV-sensitive social protection for vulnerable young women in East and Southern Africa: A systematic review

2021

Introduction: Social protection programmes are considered HIV-sensitive when addressing risk, vulnerability or impact of HIV infection. Socio-economic interventions, like livelihood and employability programmes, address HIV vulnerabilities like poverty and gender inequality....

HIV self-testing with digital supports as the new paradigm: A systematic review of global evidence (2010–2021)

2021

BACKGROUND: HIV self-testing (HIVST) is recommended by the WHO as an innovative strategy to reach UNAIDS targets to end HIV by 2030. HIVST with digital supports is defined as the...

TLR-agonist mediated enhancement of antibody-dependent effector functions as strategy for an HIV-1 cure

2021

BACKGROUND: The current treatment for HIV-1 is based on blocking various stages in the viral replication cycle using combination antiretroviral therapy (ART). Even though ART effectively controls the infection, it...

Health programmes and services addressing the prevention and management of infectious diseases in people who inject drugs in Canada: A systematic integrative review

2021

OBJECTIVES: People who inject drugs (PWID) experience a high burden of injection drug use-related infectious disease and challenges in accessing adequate care. This study sought to identify programmes and services...

The influence of HLA/HIV genetics on the occurrence of elite controllers and a need for therapeutics geotargeting view

2021

The interaction of HIV-1, human leukocyte antigen (HLA), and elite controllers (EC) compose a still intricate triad. Elite controllers maintain a very low viral load and a normal CD4 count,...

Cardiovascular disease risk among transgender people with HIV

2021

PURPOSE OF REVIEW: Transgender individuals are at disproportionate risk for HIV infection, with prevalence rates highest among transgender women of color. Antiretroviral therapy (ART)-treated people with HIV (PWH) are at...

Effects of resistance training on muscle strength, body composition and immune-inflammatory markers in people living with HIV: A systematic review and meta-analysis of randomized controlled trials

2021

Purpose: The purpose of this review is to evaluate the effect of resistance training (RT) as a unique intervention on muscle strength, body composition, and immune-inflammatory markers in people living...

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