Category Archives: Prevention, Engagement and Care Cascade

Impact of community pharmacist-led interventions in chronic disease management on clinical, utilization, and economic outcomes: An umbrella review

2019

BACKGROUND: Chronic disease represents a significant burden to the United States (US) health care system, with approximately 50% of all adults in the US having one or more chronic disease...

The PrEP care continuum among cisgender women who sell sex and/or use drugs globally: A systematic review

2019

HIV prevalence among cisgender female sex workers (FSW) and/or women who use drugs (WWUD) is substantially higher compared to similarly aged women. Consistent with PRISMA guidelines, we conducted the first...

Efficacy and safety of raltegravir-based dual therapy in AIDS patients: A meta-analysis of randomized controlled trials

2019

Background: The life expectancy for HIV-infected individuals has improved dramatically because of improvements in antiretroviral therapy (ART). Today, a simplified two-drug regimen enhances adherence and treatment satisfaction by reducing adverse...

Burnout among service providers addressing substance use disorders

2019

Key take-home messages Main burnout components experienced among service providers addressing substance use disorders include emotional exhaustion (feeling drained of all available emotional capacity), depersonalization (experiencing cynicism, helplessness and detachment),...

Crowdsourcing in health and medical research: A systematic review

2020

BACKGROUND: Crowdsourcing is used increasingly in health and medical research. Crowdsourcing is the process of aggregating crowd wisdom to solve a problem. The purpose of this systematic review is to...

HIV non-occupational post exposure prophylaxis in Nigeria: A systematic review of research evidence and practice

2019

Background: Although non-occupational Human Immunodeficiency Virus (HIV) post-exposure prophylaxis (nPEP) has been proven to be efficacious in preventing HIV, it remains an underutilized prevention strategy in Nigeria. We aimed to...

HIV viral resuppression following an elevated viral load: A systematic review and meta-analysis

2019

INTRODUCTION: Guidelines for antiretroviral therapy recommend enhanced adherence counselling be provided to individuals with an initial elevated viral load before making a decision whether to switch antiretroviral regimen. We undertook...

The risk of HIV among women after acquiring a sexually transmitted infection (STI) and considerations for their use of PrEP

2020

Key take-home messages A recent study in the U.S. found that most women who were diagnosed with HIV did not have a reported STI in the past. Another U.S. study...

HIV/AIDS treatment failure and associated factors in Ethiopia: Meta-analysis

2020

BACKGROUND: The national burden of human immunodeficiency virus treatment failure and associated factors in the Ethiopian context is required to provide evidence towards a renewed ambitious future goal. METHODS: We...

Burden of anemia and its association with HAART in HIV infected children in Ethiopia: A systematic review and meta-analysis

2019

BACKGROUND: Anemia is a common problem in HIV (human immunodeficiency virus) infected patients, and is associated with decreased functional capacity and quality of life. Ethiopia is one of the countries...

Vaginal ring acceptability and related preferences among women in low- and middle-income countries: A systematic review and narrative synthesis

2019

The vaginal ring (VR) is a female-initiated drug-delivery platform used for different indications, including HIV pre-exposure prophylaxis (PrEP). We conducted a systematic review of VR acceptability, values and preferences among...

Loss to follow-up from antiretroviral therapy clinics: A systematic review and meta-analysis of published studies in South Africa from 2011 to 2015

2019

Background: South Africa has the largest antiretroviral therapy (ART) programme in the world. To optimise programme outcomes, it is critical that patients are retained in care and that retention is...

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