Category Archives: Prevention, Engagement and Care Cascade
Impact of community pharmacist-led interventions in chronic disease management on clinical, utilization, and economic outcomes: An umbrella review
BACKGROUND: Chronic disease represents a significant burden to the United States (US) health care system, with approximately 50% of all adults in the US having one or more chronic disease...
The PrEP care continuum among cisgender women who sell sex and/or use drugs globally: A systematic review
HIV prevalence among cisgender female sex workers (FSW) and/or women who use drugs (WWUD) is substantially higher compared to similarly aged women. Consistent with PRISMA guidelines, we conducted the first...
Efficacy and safety of raltegravir-based dual therapy in AIDS patients: A meta-analysis of randomized controlled trials
Background: The life expectancy for HIV-infected individuals has improved dramatically because of improvements in antiretroviral therapy (ART). Today, a simplified two-drug regimen enhances adherence and treatment satisfaction by reducing adverse...
Burnout among service providers addressing substance use disorders
Key take-home messages Main burnout components experienced among service providers addressing substance use disorders include emotional exhaustion (feeling drained of all available emotional capacity), depersonalization (experiencing cynicism, helplessness and detachment),...
HIV non-occupational post exposure prophylaxis in Nigeria: A systematic review of research evidence and practice
Background: Although non-occupational Human Immunodeficiency Virus (HIV) post-exposure prophylaxis (nPEP) has been proven to be efficacious in preventing HIV, it remains an underutilized prevention strategy in Nigeria. We aimed to...
HIV viral resuppression following an elevated viral load: A systematic review and meta-analysis
INTRODUCTION: Guidelines for antiretroviral therapy recommend enhanced adherence counselling be provided to individuals with an initial elevated viral load before making a decision whether to switch antiretroviral regimen. We undertook...
Burden of anemia and its association with HAART in HIV infected children in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Anemia is a common problem in HIV (human immunodeficiency virus) infected patients, and is associated with decreased functional capacity and quality of life. Ethiopia is one of the countries...
Vaginal ring acceptability and related preferences among women in low- and middle-income countries: A systematic review and narrative synthesis
The vaginal ring (VR) is a female-initiated drug-delivery platform used for different indications, including HIV pre-exposure prophylaxis (PrEP). We conducted a systematic review of VR acceptability, values and preferences among...
Loss to follow-up from antiretroviral therapy clinics: A systematic review and meta-analysis of published studies in South Africa from 2011 to 2015
Background: South Africa has the largest antiretroviral therapy (ART) programme in the world. To optimise programme outcomes, it is critical that patients are retained in care and that retention is...