Category Archives: Prevention, Engagement and Care Cascade

The influence of HLA/HIV genetics on the occurrence of elite controllers and a need for therapeutics geotargeting view

2021

The interaction of HIV-1, human leukocyte antigen (HLA), and elite controllers (EC) compose a still intricate triad. Elite controllers maintain a very low viral load and a normal CD4 count,...

Cardiovascular disease risk among transgender people with HIV

2021

PURPOSE OF REVIEW: Transgender individuals are at disproportionate risk for HIV infection, with prevalence rates highest among transgender women of color. Antiretroviral therapy (ART)-treated people with HIV (PWH) are at...

Effects of resistance training on muscle strength, body composition and immune-inflammatory markers in people living with HIV: A systematic review and meta-analysis of randomized controlled trials

2021

Purpose: The purpose of this review is to evaluate the effect of resistance training (RT) as a unique intervention on muscle strength, body composition, and immune-inflammatory markers in people living...

Harm reduction for smokers living with HIV

2021

Tobacco use is now a leading cause of death in people living with HIV in the USA. Increasing cessation rates in this group is a public health priority, yet the...

Assessing HIV and overdose risks for people who use drugs exposed to compulsory drug abstinence programs (CDAP): A systematic review and meta-analysis

2021

Background: Evidence supports integrating drug use treatment, harm reduction, and HIV prevention services to address dual epidemics of drug use disorders and HIV. These dual epidemics have spurred a rise in...

Strategies for the diagnosis and management of meningitis in HIV-infected adults in resource limited settings

2021

INTRODUCTION: The incidence of human immunodeficiency virus-1 (HIV-1) associated meningitis has been declining in the post-combination antiretroviral treatment (ART) era, although survival rates remain low for the common causes like...

Pharmacy-based interventions to increase use of HIV pre-exposure prophylaxis in the United States: A scoping review

2021

HIV pre-exposure prophylaxis (PrEP) remains underutilized in the U.S. Since greater than 85% of PrEP prescriptions are filled at commercial pharmacies, pharmacists are uniquely positioned to increase PrEP use. This...

NK cell-based therapies for HIV infection: Investigating current advances and future possibilities

2021

NK cells are well-known for their antiviral functions. Also, their role in HIV has been well established, with rapid responses elicited during early HIV infection. Most immune cells including CD4(+)...

Testing for saturation in qualitative evidence syntheses: An update of HIV adherence in Africa

2021

BACKGROUND: A systematic review of randomised trials may be conclusive signalling no further research is needed; or identify gaps requiring further research that may then be included in review updates....

Post-immigration factors affecting retention in HIV care and viral suppression in Latin American and Caribbean immigrant populations in the United States: A systematic review

2021

Objectives: To reduce disparities in HIV care outcomes among Latin American and Caribbean (LAC) immigrants living with HIV in the U.S., it is necessary to identify factors influencing HIV care in...

Non-vertical exposures to HIV, HBV and HCV infection in children and adolescents-risk of infection, standards of care and postexposure prophylaxis

2021

INTRODUCTION: in the review, we aimed to present current knowledge about the risk of infection, standards of care, and postexposure prophylaxis (PEP) in pediatric patients after non-vertical exposures to HIV,...

Coordinating systems of care for HIV and opioid use disorder: A systematic review of enablers and barriers to integrated service access, and systems and tools required for implementation

2021

Individuals who have HIV who also use drugs experience increased age-matched morbidity and mortality in comparison with those with HIV who do not use drugs. A systematic review was conducted...

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