Category Archives: Prevention
Possible prevention of neurodevelopmental consequences of vertical HIV transmission in early childhood? A systematic review
BACKGROUND: Children infected with the Human Immunodeficiency Virus (HIV) exhibit the lowest neurodevelopmental scores. Mother-to-child-transmission prevention include perinatally and early antiretroviral therapy (ART) although long-term effects of in utero exposure...
Oral pre-exposure prophylaxis initiation, continuation and adherence among pregnant and postpartum women receiving antenatal and postnatal care: A systematic review
INTRODUCTION: In 2023, one-fourth of new HIV acquisitions in children globally resulted from vertical transmission following incident HIV during pregnancy or breastfeeding. Oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil and...
Motivations, facilitators, and barriers of donation-based interventions in HIV and sexually transmitted infection research: A systematic review
IMPORTANCE: Donation-based prosocial interventions involve someone receiving a free health service and then distributing or donating to support health services for others; examples within the HIV and sexually transmitted infection...
Interventions to support breastfeeding among mothers living with HIV: A systematic review and meta-analysis of randomized controlled trials
BACKGROUND: Breastfeeding improves infant survival, especially in low-resource settings. Although the risk of postnatal transmission is below 1% among virologically suppressed mothers living with HIV, exclusive breastfeeding (EBF) rates and...
Effectiveness of conditional cash transfers for uptake and retention in HIV prevention of mother-to-child transmission services in low- and middle-income countries: A systematic review and meta-analysis
OBJECTIVE: The objective of this systematic review was to synthesize the best available evidence on the effectiveness of conditional cash transfers for the uptake and retention in prevention of mother-to-child...
Maternal HIV infection and antiretroviral therapy in pregnancy: Implications for vertical transmission, fetal safety, and long-term infant outcomes
HIV mother-to-child transmission (MTCT) continues to pose a significant public health challenge, especially in regions with limited resources, although the worldwide distribution of antiretroviral therapy (ART) has drastically lowered the...
Oral pre-exposure prophylaxis retention among men who have sex with men and transgender persons: Systematic review and meta-analysis
Successful implementation of oral pre-exposure prophylaxis (PrEP) requires retention in PrEP care among those with an increased likelihood of HIV. This study aimed to estimate the proportion of retention on...
A scoping review of grey zone use for transfusion-transmitted infection screening among blood donors
BACKGROUND AND OBJECTIVES: Screening for transfusion-transmitted infections (TTIs) among blood donors is done using qualitative screening assays. Screening values that are close to cut-off values lie in the uncertainty zone,...
Integration of mental health and HIV service delivery in low- and middle-income countries: A systematic review of effectiveness
Human immunodeficiency virus (HIV) and mental health have complex, bidirectional impacts. Integrated service delivery, especially in low- and middle-income countries (LMICs) where resources are most limited and the burden of...
Seroprevalence of transfusion-transmitted infections among blood donors in India: A systematic review and meta-analysis
BACKGROUND AND OBJECTIVES: Blood transfusion is essential in healthcare but carries inherent risks of human immunodeficiency virusAÿ(HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and malaria transmission. National...
Immunogenicity and safety of the booster COVID-19 vaccine among people with HIV: A systematic review and meta-analysis
Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...
