Category Archives: Prevention
Critical review: Review of the efficacy, safety, and pharmacokinetics of raltegravir in pregnancy
Raltegravir was previously considered an alternative antiretroviral in pregnancy because of limited data, but recent pregnancy guidelines recommend raltegravir as a preferred integrase treatment option. Data from published articles and...
Trends in sexual behavior among men who have sex with men (MSM) in high-income countries, 1990-2013: A systematic review
HIV diagnoses among men who have sex with men (MSM) have been increasing in several high-income countries. A better understanding of the sexual behavior trends among MSM can be useful...
HIV-free survival at 12-24 months in breastfed infants of HIV-infected women on antiretroviral treatment
OBJECTIVE: To provide estimates of HIV-free survival at 12-24 months in breastfed children by maternal ART (6 months or lifelong) to inform WHO HIV and Infant Feeding guidelines. METHODS: Eighteen...
A global estimate of the acceptability of pre-exposure prophylaxis for HIV among men who have sex with men: A systematic review and meta-analysis
Pre-exposure prophylaxis (PrEP) is a new biomedical intervention for HIV prevention. This study systematically reviews the acceptability of PrEP among men who have sex with men (MSM) worldwide. We searched...
Behavioural disinhibition in the general population during the antiretroviral therapy roll-out in Sub-Saharan Africa: Systematic review and meta-analysis
Objectives: Improved life expectancy and reduced transmission probabilities due to ART may result in behavioural disinhibition – that is an increase in sexual risk behaviour in response to a perceived lower...
Improving outpatient implementation of preexposure prophylaxis in men who have sex with men
BACKGROUND AND PURPOSE: Preexposure prophylaxis (PrEP) has been shown to decrease the transmission of human immunodeficiency virus (HIV) when used in high-risk populations including men who have sex with men....
Systematic review of sex work interventions in sub-Saharan Africa: Examining combination prevention approaches
OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan...
Neighborhood environments and sexual risk behaviors for HIV infection among U.S. women: A systematic review
Empirical evidence indicates that aspects of the neighborhood environment may affect HIV prevention efforts. Therefore, the neighborhood environment should be considered when implementing prevention interventions. However, much of the empirical...
Effectiveness of needle and syringe programmes in people who inject drugs – An overview of systematic reviews
BACKGROUND: Needle and syringe programmes (NSP) are a critical component of harm reduction interventions among people who inject drugs (PWID). Our primary objective was to summarize the evidence on the...
A systematic review and meta-analysis of psychosocial interventions to reduce drug and sexual blood borne virus risk behaviours among people who inject drugs
Opiate substitution treatment and needle exchanges have reduced blood borne virus (BBV) transmission among people who inject drugs (PWID). Psychosocial interventions could further prevent BBV. A systematic review and meta-analysis...
A critical review of the effectiveness of educational interventions applied in HIV/AIDS prevention
OBJECTIVE: A critical review of issues around the effectiveness of educational approaches applied in the field of HIV/AIDS prevention. METHODS: Published papers, systematic reviews and technical reports were reviewed. RESULTS:...
