Category Archives: Prevention
Female and younger subjects have lower adherence in PrEP trials: A meta-analysis with implications for the uptake of PrEP service to prevent HIV
OBJECTIVE: To estimate the medicine-taking compliance (MTC) level, explore its facilitators and barriers, and quantify the association between MTC level and pre-exposure prophylaxis (PrEP) protective efficacy in individuals at risk...
Understanding the experiences of married Southern African women in protecting themselves from HIV/AIDS: A systematic review and meta-synthesis
BACKGROUND: Whilst marriage has been repeatedly identified in the literature as an HIV risk factor amongst Southern African women, not much is known about women’s perception of their role, experiences...
Host molecular factors and viral genotypes in the mother-to-child HIV-1 transmission in Sub-Saharan Africa
Maternal viral load and immune status, timing and route of delivery, viral subtype, and host genetics are known to influence the transmission, acquisition and disease progression of human immunodeficiency virus-1...
The sexual lives of people with disabilities within low- and middle-income countries: A scoping study of studies published in English
BACKGROUND: Although approximately 80% of the global population of people with disabilities reside in low- and middle-income countries (LMICs), very little is known about their sexual lives due to a...
Optimal anti-retroviral prophylaxis in infants at high-risk of acquiring human immunodeficiency virus: A systematic review
INTRODUCTION: The risk of perinatal HIV infection can be dramatically reduced through maternal antiretroviral therapy (ART) and infant antiretroviral (ARV) postnatal prophylaxis. The 2013 WHO guidelines recommended four to six...
HIV risk-reduction prevention interventions targeting African American adolescent women
African American young women are overwhelmingly disproportionately burdened by HIV/AIDS in the United States today. The purpose of the current systematic review was to identify the characteristics of efficacious HIV...
Quantifying the harms and benefits from serosorting among HIV-negative gay and bisexual men: A systematic review and meta-analysis
We conducted a systematic review and meta-analysis of the association between serosorting and HIV infection among HIV-negative men who have sex with men (MSM). Compared to no condomless anal sex...
Awareness and willingness to use HIV pre-exposure prophylaxis among men who have sex with men in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: To facilitate provision of pre-exposure prophylaxis (PrEP) in low- and middle-income countries (LMIC), a better understanding of potential demand and user preferences is required. This review assessed awareness and...
Trends in sexual behavior among men who have sex with men (MSM) in high-income countries, 1990-2013: A systematic review
HIV diagnoses among men who have sex with men (MSM) have been increasing in several high-income countries. A better understanding of the sexual behavior trends among MSM can be useful...
Comprehensive review of the evidence regarding the effectiveness of community-based primary health care in improving maternal, neonatal and child health: 1. rationale, methods and database description
BACKGROUND: Community-based primary health care (CBPHC) is an approach used by health programs to extend preventive and curative health services beyond health facilities into communities and even down to households....
