Category Archives: Prevention
Understanding the experiences of married Southern African women in protecting themselves from HIV/AIDS: A systematic review and meta-synthesis
BACKGROUND: Whilst marriage has been repeatedly identified in the literature as an HIV risk factor amongst Southern African women, not much is known about women’s perception of their role, experiences...
Female and younger subjects have lower adherence in PrEP trials: A meta-analysis with implications for the uptake of PrEP service to prevent HIV
OBJECTIVE: To estimate the medicine-taking compliance (MTC) level, explore its facilitators and barriers, and quantify the association between MTC level and pre-exposure prophylaxis (PrEP) protective efficacy in individuals at risk...
The sexual lives of people with disabilities within low- and middle-income countries: A scoping study of studies published in English
BACKGROUND: Although approximately 80% of the global population of people with disabilities reside in low- and middle-income countries (LMICs), very little is known about their sexual lives due to a...
Host molecular factors and viral genotypes in the mother-to-child HIV-1 transmission in Sub-Saharan Africa
Maternal viral load and immune status, timing and route of delivery, viral subtype, and host genetics are known to influence the transmission, acquisition and disease progression of human immunodeficiency virus-1...
HIV risk-reduction prevention interventions targeting African American adolescent women
African American young women are overwhelmingly disproportionately burdened by HIV/AIDS in the United States today. The purpose of the current systematic review was to identify the characteristics of efficacious HIV...
Optimal anti-retroviral prophylaxis in infants at high-risk of acquiring human immunodeficiency virus: A systematic review
INTRODUCTION: The risk of perinatal HIV infection can be dramatically reduced through maternal antiretroviral therapy (ART) and infant antiretroviral (ARV) postnatal prophylaxis. The 2013 WHO guidelines recommended four to six...
Quantifying the harms and benefits from serosorting among HIV-negative gay and bisexual men: A systematic review and meta-analysis
We conducted a systematic review and meta-analysis of the association between serosorting and HIV infection among HIV-negative men who have sex with men (MSM). Compared to no condomless anal sex...
Behavioural disinhibition in the general population during the antiretroviral therapy roll-out in Sub-Saharan Africa: Systematic review and meta-analysis
Objectives: Improved life expectancy and reduced transmission probabilities due to ART may result in behavioural disinhibition – that is an increase in sexual risk behaviour in response to a perceived lower...
Systematic review of sex work interventions in sub-Saharan Africa: Examining combination prevention approaches
OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan...
