Category Archives: Prevention

Brief interventions to prevent sexually transmitted infections suitable for in-service use: A systematic review

2016

BACKGROUND: Sexually transmitted infections (STIs) are more common in young people and men who have sex with men (MSM) and effective in-service interventions are needed. METHODS: A systematic review of...

New challenges in therapeutic vaccines against HIV infection

2017

INTRODUCTION: There is a growing interest in developing curative strategies for HIV infection. Therapeutic vaccines are one of the most promising approaches. We will review the current knowledge and the...

Behavioural disinhibition in the general population during the antiretroviral therapy roll-out in Sub-Saharan Africa: Systematic review and meta-analysis

2017

Objectives: Improved life expectancy and reduced transmission probabilities due to ART may result in behavioural disinhibition – that is an increase in sexual risk behaviour in response to a perceived lower...

Performance of virological testing for early infant diagnosis: A systematic review

2017

BACKGROUND: Improved access to both maternal antiretroviral therapy (ART) and infant prophylaxis may have an impact on the performance of virological assays for diagnosis of HIV infection in infants. This...

Systematic review of sex work interventions in sub-Saharan Africa: Examining combination prevention approaches

2017

OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan...

Effectiveness of needle and syringe programmes in people who inject drugs – An overview of systematic reviews

2017

BACKGROUND: Needle and syringe programmes (NSP) are a critical component of harm reduction interventions among people who inject drugs (PWID). Our primary objective was to summarize the evidence on the...

Vaccination recommendations for the adult immunosuppressed patient: A systematic review and comprehensive field synopsis

2017

BACKGROUND: Immunosuppressed patients are at risk of severe viral infections-related complications. National and international vaccination guidelines have been developed to decrease the mortality risk associated with these infections. However, a...

Neighborhood environments and sexual risk behaviors for HIV infection among U.S. women: A systematic review

2017

Empirical evidence indicates that aspects of the neighborhood environment may affect HIV prevention efforts. Therefore, the neighborhood environment should be considered when implementing prevention interventions. However, much of the empirical...

A critical review of the effectiveness of educational interventions applied in HIV/AIDS prevention

2015

OBJECTIVE: A critical review of issues around the effectiveness of educational approaches applied in the field of HIV/AIDS prevention. METHODS: Published papers, systematic reviews and technical reports were reviewed. RESULTS:...

The potential cost-effectiveness of HIV vaccines: A systematic review

2017

OBJECTIVE: The aim of this paper was to review and compare HIV vaccine cost-effectiveness analyses and describe the effects of uncertainty in model, methodology, and parameterization. METHODS: We systematically searched...

A systematic review and meta-analysis of psychosocial interventions to reduce drug and sexual blood borne virus risk behaviours among people who inject drugs

2017

Opiate substitution treatment and needle exchanges have reduced blood borne virus (BBV) transmission among people who inject drugs (PWID). Psychosocial interventions could further prevent BBV. A systematic review and meta-analysis...

Postnatal HIV transmission in breastfed infants of HIV-infected women on ART: A systematic review and meta-analysis

2017

INTRODUCTION: To systematically review the literature on mother-to-child transmission in breastfed infants whose mothers received antiretroviral therapy and support the process of updating the World Health Organization infant feeding guidelines...

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