Category Archives: Prevention

A comprehensive review of reviews of school-based interventions to improve sexual-health

2016

OBJECTIVE: To systematically review systematic reviews of school-based sexual-health and relationship Education (SHRE) programmes and, thereby, identify interventions and intervention components that promote reductions in risky sexual behaviour among young...

Recent evidence for emerging digital technologies to support global HIV engagement in care

2015

Antiretroviral therapy is a powerful tool to reduce morbidity and mortality for the 35 million people living with HIV globally. However, availability of treatment alone is insufficient to meet new...

Pros and cons of circumcision: An evidence-based overview

2016

Based on three large randomized controlled trials (RCTs) conducted in Africa, it can clearly be stated that circumcision lowers the risk of infection with the human immunodeficiency virus (HIV) and...

Revisiting the understanding of “transactional sex” in sub-Saharan Africa: A review and synthesis of the literature

2016

In sub-Saharan Africa, young women ages 15-24 have more than twice the risk of acquiring HIV as their male counterparts. A growing body of epidemiological evidence suggests that the practice...

Effectiveness of pharmacy-based needle/syringe exchange programme for people who inject drugs: A systematic review and meta-analysis

2016

AIMS: To appraise the evidence critically for effectiveness of pharmacy-based needle/syringe exchange programmes (pharmacy-based NSPs) on risk behaviours (RBs), HIV/HCV prevalence and economic outcomes among people who inject drugs (PWID)....

Safety of oral tenofovir disoproxil fumarate-based pre-exposure prophylaxis for HIV prevention

2016

INTRODUCTION: Tenofovir disoproxil fumarate (TDF)-based pre-exposure prophylaxis is a novel HIV prevention strategy for individuals at increased sexual risk for HIV infection. For any biomedical prevention intervention, the bar for...

Interventions to prevent sexually transmitted infections, including HIV, among young people in low- and middle-income countries: A systematic review of the published and gray literature

2016

Sexually transmitted infections (STIs), including HIV, are prevalent among adolescents and can have lasting adverse health consequences. The objective of this review is to identify high-quality interventions and evaluations to...

How do HIV-negative individuals in sub-Saharan Africa change their sexual risk behaviour upon learning their serostatus? A systematic review

2016

OBJECTIVE: To determine whether, and how, sexual behaviour of HIV-negative individuals in sub-Saharan Africa (SSA) changes upon learning their serostatus. METHODS: We systematically reviewed the published literature using EMBASE and...

Equality in sexual health promotion: a systematic review of effective interventions for black and minority ethnic men who have sex with men

2016

BACKGROUND: Over the past decade, new diagnoses of HIV have increased eightfold among men who have sex with men (MSM) of other or of mixed ethnicity in the UK. Yet...

The effect of HIV counselling and testing on HIV acquisition in sub-Saharan Africa: A systematic review

2016

OBJECTIVES: Annually, millions of people in sub-Saharan Africa (SSA) receive HIV counselling and testing (HCT), a service designed to inform persons of their HIV status and, if HIV uninfected, reduce...

Interventions targeting sexual and reproductive health and rights outcomes of young people living with HIV: A comprehensive review of current interventions from sub-Saharan Africa

2015

BACKGROUND: A growing number of young people (ages 10-24) are living with HIV (YPLWH) in sub-Saharan Africa (SSA). These YPLWH have particular needs and challenges related to their sexual and...

Ability of HIV advocacy to modify behavioral norms and treatment impact: A systematic review

2016

BACKGROUND: HIV advocacy programs are partly responsible for the global community’s success in reducing the burden of HIV. The rising wave of the global burden of noncommunicable diseases (NCDs) has...

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