Category Archives: Prevention

Safety and efficacy of lopinavir/ritonavir during pregnancy: A systematic review

2013

The co-formulated, ritonavir-boosted protease inhibitor lopinavir is a frequently used component of HAART for treatment of HIV-infected women during pregnancy and prevention of mother-to-child transmission. We performed a systematic review...

State of the evidence: Intimate partner violence and HIV/STI risk among adolescents

2013

This paper provides a critical narrative review of the scientific literature on intimate partner violence (IPV) and risky sexual behavior as well as sexually transmitted infections (STIs) among adolescents, aged...

The association between HIV/AIDS-related knowledge and perception of risk for infection: A systematic review

2015

This systematic review tries to elucidate the association between what people know about HIV/AIDS and how they perceive their risk of infection. The initial search for articles yielded 1,595 abstracts,...

Effects of HIV antiretroviral therapy on sexual and injecting risk-taking behavior: A systematic review and meta-analysis.

2014

BACKGROUND: Increased global access and use of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) has been postulated to undermine HIV prevention efforts by changing individual risk-taking behavior. This review...

HIV, HCV, and health-related harms among women who inject drugs: Implications for prevention and treatment

2015

BACKGROUND: Although an estimated 3.5 million women inject drugs globally, women are outnumbered 4 to one by men who inject drugs and are often ignored or overlooked in the development...

Social media and HIV: A systematic review of uses of social media in HIV communication

2015

BACKGROUND: Social media, including mobile technologies and social networking sites, are being used increasingly as part of human immunodeficiency virus (HIV) prevention and treatment efforts. As an important avenue for...

Efficacy and biological safety of lopinavir/ritonavir based anti-retroviral therapy in HIV-1-infected patients: A meta-analysis of randomized controlled trials

2015

Lopinavir/ritonavir (LPV/r) is the first ritonavir-boosted protease-inhibitor used in second-line anti-retroviral treatment (ART) in resource-limited regions. To evaluate the efficacy and safety outcomes of LPV/r in treatment-naive and -experienced HIV-infected...

Voluntary medical male circumcision for HIV prevention and early resumption of sexual activity: A literature review

2015

A number of programs have focused on scale-up and implementation research regarding voluntary medical male circumcision; however, there is limited research with regard to factors and strategies related to abstinence...

The cost and impact of scaling up pre-exposure prophylaxis for HIV prevention: A systematic review of cost-effectiveness modelling studies

2013

BACKGROUND: Cost-effectiveness studies inform resource allocation, strategy, and policy development. However, due to their complexity, dependence on assumptions made, and inherent uncertainty, synthesising, and generalising the results can be difficult....

Sexual risk reduction interventions for HIV prevention among South African youth: A meta-analytic review

2013

OBJECTIVES: To examine the efficacy of sexual risk reduction interventions among South African youth. METHODS: Electronic databases were searched to identify studies published between 2007 and early 2013. Studies were...

Behavioral interventions improve condom use and HIV testing uptake among female sex workers in China: A systematic review and meta-analysis

2015

Condomless commercial sex work is a common mode of HIV transmission in China. This study systematically reviews the impacts of behavioral interventions on condom use and HIV testing uptake among...

Is there scope for cost savings and efficiency gains in HIV services? A systematic review of the evidence from low- and middle-income countries

2014

OBJECTIVE: To synthesize the data available–on costs, efficiency and economies of scale and scope–for the six basic programmes of the UNAIDS Strategic Investment Framework, to inform those planning the scale-up...

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