Category Archives: Prevention
The association between HIV/AIDS-related knowledge and perception of risk for infection: A systematic review
This systematic review tries to elucidate the association between what people know about HIV/AIDS and how they perceive their risk of infection. The initial search for articles yielded 1,595 abstracts,...
Effects of HIV antiretroviral therapy on sexual and injecting risk-taking behavior: A systematic review and meta-analysis.
BACKGROUND: Increased global access and use of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) has been postulated to undermine HIV prevention efforts by changing individual risk-taking behavior. This review...
Starter packs versus full prescription of antiretroviral drugs for postexposure prophylaxis: A systematic review
BACKGROUND: The provision of starter packs for human immunodeficiency virus postexposure prophylaxis (PEP) is practiced in many settings to facilitate rapid initiation by nonexperts and encourage adherence. However, the impact...
Sexual risk reduction interventions for HIV prevention among South African youth: A meta-analytic review
OBJECTIVES: To examine the efficacy of sexual risk reduction interventions among South African youth. METHODS: Electronic databases were searched to identify studies published between 2007 and early 2013. Studies were...
Behavioral interventions improve condom use and HIV testing uptake among female sex workers in China: A systematic review and meta-analysis
Condomless commercial sex work is a common mode of HIV transmission in China. This study systematically reviews the impacts of behavioral interventions on condom use and HIV testing uptake among...
Is there scope for cost savings and efficiency gains in HIV services? A systematic review of the evidence from low- and middle-income countries
OBJECTIVE: To synthesize the data available–on costs, efficiency and economies of scale and scope–for the six basic programmes of the UNAIDS Strategic Investment Framework, to inform those planning the scale-up...
Cobicistat: A new opportunity in the treatment of HIV disease?
INTRODUCTION: Cobicistat (Cobi), a selective novel CYP3A4 inhibitor, is an orally administered, non-antiretroviral pharmacokinetic enhancer which boosts the plasma levels of several drugs, including HIV-1 protease inhibitors and the integrase...
Choice of antiretroviral drugs for postexposure prophylaxis for children: A systematic review
BACKGROUND: This systematic review aimed to assess the safety and efficacy of antiretroviral options for postexposure prophylaxis (PEP). Recognizing the limited data on the safety and efficacy of antiretroviral drugs...
Systematic assessment of condom use measurement in evaluation of HIV prevention interventions: Need for standardization of measures
When evaluating HIV prevention interventions, condom use is a common outcome measure used to assess changes in HIV-related behaviors; however, no widely accepted standards exist for its measurement. Using systematic...
