Category Archives: Prevention
Cobicistat: A new opportunity in the treatment of HIV disease?
INTRODUCTION: Cobicistat (Cobi), a selective novel CYP3A4 inhibitor, is an orally administered, non-antiretroviral pharmacokinetic enhancer which boosts the plasma levels of several drugs, including HIV-1 protease inhibitors and the integrase...
Choice of antiretroviral drugs for postexposure prophylaxis for children: A systematic review
BACKGROUND: This systematic review aimed to assess the safety and efficacy of antiretroviral options for postexposure prophylaxis (PEP). Recognizing the limited data on the safety and efficacy of antiretroviral drugs...
Effective approaches for programming to reduce adolescent vulnerability to HIV infection, HIV risk, and HIV-related morbidity and mortality: A systematic review of systematic reviews
BACKGROUND: In 2012, an estimated 2.1 million adolescents were living with HIV. Though there are effective interventions to prevent and treat HIV infection, adolescents face specific barriers in accessing them....
Is the sexual behaviour of young people in sub-Saharan Africa influenced by their peers? A systematic review
Adolescents in sub-Saharan Africa are highly vulnerable to HIV, other sexually transmitted infections (STIs) and unintended pregnancies. Evidence for the effectiveness of individual behaviour change interventions in reducing incidence of...
Computer-based HIV adherence promotion interventions: A systematic review
Researchers have instituted a range of methodologies to increase access to HIV adherence interventions. This article reviews studies published through January 2014 utilizing computer-based delivery of such interventions to persons...
Choice of antiretroviral drugs for postexposure prophylaxis for adults and adolescents: A systematic review
BACKGROUND: The choice of preferred regimens for human immunodeficiency virus postexposure prophylaxis (PEP) has evolved over the last 2 decades as more data have become available regarding the safety and...
Factors underlying the success of behavioral HIV-prevention interventions for adolescents: a meta-review.
The purpose of this meta-review was to identify characteristics of successful HIV prevention interventions for adolescents based on quantitative (i.e., meta-analyses) and qualitative reviews published to date, and to inform...
Acculturation and HIV-related sexual behaviours among international migrants: A systematic review and meta-analysis
This review examines the global literature regarding the relationship between acculturation and HIV-related sexual behaviours among international migrants. Seventy-nine articles published in English-language journals prior to July 2012 met the...
Targeting the SAVA (Substance Abuse, Violence, and AIDS) syndemic among women and girls: A global review of epidemiology and integrated interventions
OBJECTIVES: Multiple pathways link gender-based violence (GBV) to HIV and other sexually transmitted infections among women and girls who use or inject drugs. The aim of this article is to...
