Category Archives: Prevention

Cobicistat: A new opportunity in the treatment of HIV disease?

2014

INTRODUCTION: Cobicistat (Cobi), a selective novel CYP3A4 inhibitor, is an orally administered, non-antiretroviral pharmacokinetic enhancer which boosts the plasma levels of several drugs, including HIV-1 protease inhibitors and the integrase...

Choice of antiretroviral drugs for postexposure prophylaxis for children: A systematic review

2015

BACKGROUND: This systematic review aimed to assess the safety and efficacy of antiretroviral options for postexposure prophylaxis (PEP). Recognizing the limited data on the safety and efficacy of antiretroviral drugs...

Effectiveness of ART and condom use for prevention of sexual HIV transmission in serodiscordant couples: A systematic review and meta-analysis

2014

BACKGROUND: Consistent and correct condom use and suppressive antiretroviral therapy for the infected partner are two of the primary strategies recommended for prevention of heterosexual HIV transmission in serodiscordant couples...

Contraceptive methods and risk of HIV acquisition or female-to-male transmission

2014

Effective family planning with modern contraception is an important intervention to prevent unintended pregnancies which also provides personal, familial, and societal benefits. Contraception is also the most cost-effective strategy to...

The effectiveness of community interventions targeting HIV and AIDS prevention at young people in developing countries

2006

OBJECTIVE: To identify successful HIV/AIDS prevention interventions targeting youths and delivered in geographically bounded communities (for example, rural villages, urban settlements or neighbourhoods) in developing countries. METHODS: A systematic review...

Effectiveness of interventions promoting HIV serostatus disclosure to sexual partners: A systematic review

2015

Disclosure of HIV serostatus to sexual partners is mandated within certain states in the United States and other countries. Despite these laws implemented and public health efforts to increase disclosure,...

Pharmacologic management of human immunodeficiency virus wasting syndrome

2014

Pharmacologic interventions for human immunodeficiency virus (HIV) wasting have been studied since the 1990s, but the results of these interventions have been difficult to compare because the studies used different...

Choice of antiretroviral drugs for postexposure prophylaxis for adults and adolescents: A systematic review

2015

BACKGROUND: The choice of preferred regimens for human immunodeficiency virus postexposure prophylaxis (PEP) has evolved over the last 2 decades as more data have become available regarding the safety and...

Brief sexuality communication-a behavioural intervention to advance sexually transmitted infection/HIV prevention: A systematic review

2014

BACKGROUND: Throughout the last decade substantial research has been undertaken to develop evidence-based behaviour change interventions for sexual health promotion. Primary care could provide an opportunistic entry for brief sexual...

HIV sexual risk behavior in older black women: A systematic review

2015

BACKGROUND: Human immunodeficiency virus (HIV) is a major public health concern in the United States, particularly among older Black women who comprise approximately 40% of the newly diagnosed cases among...

HIV sexual risk reduction interventions for women: A review

1996

AIDS has emerged as a serious public health threat for women. Reducing the risk for HIV infection among sexually active women requires the adoption of preventive strategies that effectively inhibit...

A systematic review of recent smartphone, Internet and Web 2.0 interventions to address the HIV continuum of care

2015

eHealth, mHealth and “Web 2.0” social media strategies can effectively reach and engage key populations in HIV prevention across the testing, treatment, and care continuum. To assess how these tools...

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