Category Archives: Prevention

Efficacy of behavioral interventions to increase condom use and reduce sexually transmitted infections: A meta-analysis, 1991 to 2010

2011

Objective: In the absence of an effective HIV vaccine, safer sexual practices are necessary to avert new infections. Therefore, we examined the efficacy of behavioral interventions to increase condom use...

The effectiveness of opioid maintenance treatment in prison settings: A systematic review

2012

AIMS: To review evidence on the effectiveness of opioid maintenance treatment (OMT) in prison and post-release. METHODS: Systematic review of experimental and observational studies of prisoners receiving OMT regarding treatment...

Interventions to improve the health of the homeless: A systematic review

2005

BACKGROUND: Homelessness is a widespread problem in the United States. The primary goal of this systematic review is to provide guidance in the development and organization of programs to improve...

Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

2005

BACKGROUND: Mother-to-child transmission (MTCT) of HIV is the dominant mode of acquisition of HIV infection for children, currently resulting in more than 2000 new paediatric HIV infections each day worldwide....

Safety of efavirenz in the first trimester of pregnancy: An updated systematic review and meta-analysis

2011

Evidence of the risk of birth defects with efavirenz use is limited. We updated a meta-analysis of birth defects in infants with first trimester efavirenz exposure up to July 2011....

Vaginal disinfection during labour for reducing the risk of mother-to-child transmission of HIV infection

2002

BACKGROUND: Mother-to-child transmission (MTCT) of HIV infection is one of the most tragic consequences of the HIV epidemic, especially in resource-limited countries, resulting in about 650 000 new paediatric HIV...

Effects of postnatal interventions for the reduction of vertical HIV transmission on infant growth and non-HIV infections: A systematic review

2013

INTRODUCTION: Guidelines in resource-poor settings have progressively included interventions to reduce postnatal HIV transmission through breast milk. In addition to HIV-free survival, infant growth and non-HIV infections should be considered....

Screening for human immunodeficiency virus in pregnant women: Evidence synthesis

2005

Context: An estimated 6,000 to 7,000 HIV-infected women give birth each year in the United States. Although the number of cases of perinatally acquired HIV infection has declined sharply in...

Hormonal contraceptive use and female-to-male HIV transmission: A systematic review of the epidemiologic evidence

2013

OBJECTIVE: To systematically review epidemiologic evidence assessing whether hormonal contraception alters the risk of HIV transmission from an HIV-positive woman to an HIV-negative male partner. DESIGN: Systematic review. METHODS: We...

Improving the prevention, diagnosis and treatment of TB among people living with HIV: The role of operational research

2011

Operational research is necessary to improve the access to and delivery of tuberculosis prevention, diagnosis and treatment interventions for people living with HIV. We conducted an extensive review of the...

Sexual risk reduction for persons living with HIV: Research synthesis of randomized controlled trials, 1993 to 2004

2006

OBJECTIVE: To conduct a meta-analytic review of interventions to reduce HIV individuals’ sexual risk. DESIGN: Studies were included if they examined a deliberate sexual risk-reduction strategy in a sample that...

Effectiveness of female controlled barrier methods in preventing sexually transmitted infections and HIV: Current evidence and future research directions

2005

OBJECTIVES: To evaluate evidence for the effectiveness of female controlled physical and chemical barrier methods in preventing STI/HIV transmission, to examine recent reviews on microbicide development, and to highlight promising...

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