Category Archives: Prevention
HIV prevention for South African youth: which interventions work? A systematic review of current evidence
BACKGROUND: In South Africa, HIV prevalence among youth aged 15-24 is among the world’s highest. Given the urgent need to identify effective HIV prevention approaches, this review assesses the evidence...
Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials
Objective: To conduct a meta-analytic review of HIV interventions for people living with HIV (PLWH) to determine their overall efficacy in reducing HIV risk behaviours and identify intervention characteristics associated...
Can computer-mediated interventions change theoretical mediators of safer sex? A meta-analysis
The purpose of this study was to conduct a meta-analysis of computer-mediated interventions (CMIs) aimed at changing theoretical mediators of safer sex. Meta-analytic aggregation of effect sizes from k =...
An international systematic review and meta-analysis of multisession psychosocial interventions compared with educational or minimal interventions on the HIV sex risk behaviors of people who use drugs
This systematic review and meta-analysis examines the effectiveness of multisession psychosocial interventions compared with educational interventions and minimal interventions in reducing sexual risk in people who use drugs (51 studies;...
Effects of HIV-prevention interventions for samples with higher and lower percents of Latinos and Latin Americans: A meta-analysis of change in condom use and knowledge
This meta-analysis (N=110,092) assessed the efficacy of HIV-prevention interventions across samples with higher and lower concentrations of Latinos/Latin Americans. Findings indicated that groups with higher percents of Latinos increased condom...
A decade in review: Building on the experiences of past adolescent STI/HIV interventions to optimise future prevention efforts
The major purpose of this article is to systematically review and synthesise empirical findings from selected adolescent STI/HIV interventions conducted in the United States between 1994 and 2004. Specifically, the...
Brief report: Methadone treatment of injecting opioid users for prevention of HIV infection
OBJECTIVE: To assess the effects of oral substitution treatment for opioid-dependent injecting drug users on HIV risk behaviors and infections. DATA SOURCES: Multiple electronic databases were searched. Reference lists of...
Can hepatitis C virus prevalence be used as a measure of injection-related human immunodeficiency virus risk in populations of injecting drug users? An ecological analysis
BACKGROUND: Human immunodeficiency virus (HIV) outbreaks occur among injecting drug users (IDUs), but where HIV is low insight is required into the future risk of increased transmission. The relationship between...
Considerations for implementing oral preexposure prophylaxis: A literature review
Oral preexposure prophylaxis (PrEP) is in its infancy as an approved biomedical intervention; therefore, research is needed to understand the issues surrounding its implementation. The purpose of this literature review...
Nonoxynol-9 spermicide for prevention of vaginally acquired HIV and other sexually transmitted infections: Systematic review and meta-analysis of randomised controlled trials including more than 5000 women
We aimed to determine the effectiveness of the vaginally administered spermicide nonoxynol-9 (N-9) among women for the prevention of HIV and other sexually transmitted infections (STIs). We did a systematic...
