Category Archives: Prevention
HIV transmission risk through anal intercourse: Systematic review, meta-analysis and implications for HIV prevention
BACKGROUND: The human immunodeficiency virus (HIV) infectiousness of anal intercourse (AI) has not been systematically reviewed, despite its role driving HIV epidemics among men who have sex with men (MSM)...
HIV status in discordant couples in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Most couples affected by HIV/AIDS in sub-Saharan Africa live in discordant relationships. Men are thought to be the index case in most relationships, and most social marketing and awareness...
Effectiveness of HIV prevention for youth in sub-Saharan Africa: Systematic review and meta-analysis of randomized and nonrandomized trials
Objective: Systematically assess the effectiveness of HIV-prevention interventions in changing sexual behaviour of young people (10-25 years) in sub-Saharan Africa. Methods: Three online databases were searched using prespecified terms. Additional...
Public sexual cultures: A systematic review of qualitative research investigating men’s sexual behaviors with men in public spaces
Resurgent HIV and sexually transmitted infection incidence among men who have sex with men (MSM) requires an urgent re-examination of sexual transmission sites. To these ends, we systematically review qualitative...
Abstinence-only programs for HIV infection prevention in high-income countries
Background: Abstinence-only interventions promote sexual abstinence as the only means of preventing sexual acquisition of HIV; they do not promote safer-sex strategies (e.g., condom use). Although abstinence-only programs are widespread,...
Effectiveness of sport-based HIV prevention interventions: A systematic review of the evidence.
Interest in sport as a tool for behavioral HIV prevention has grown substantially in the past decade. With dozens of organisations now using sport-based HIV prevention (SBHP) approaches and upcoming...
Efficacy of behavioral interventions to increase condom use and reduce sexually transmitted infections: A meta-analysis, 1991 to 2010
Objective: In the absence of an effective HIV vaccine, safer sexual practices are necessary to avert new infections. Therefore, we examined the efficacy of behavioral interventions to increase condom use...
Prevention of HIV among older adults: A literature review and recommendations for future research
OBJECTIVE: This study reviews the existing literature on the prevention of HIV among older adults, including universal and indicated prevention programs and prevention strategies. METHOD: A literature search was conducted...
Cost-effectiveness of antenatal HIV-testing: Reviewing its pharmaceutical and methodological aspects
This paper reviews the pharmacoeconomic aspects of antenatal testing for HIV. HIV is a retrovirus which is transmitted among humans through sexual contact, infected blood or blood products (needle sharing...
Effect of CCR5-delta32 heterozygosity on the risk of perinatal HIV-1 infection: A meta-analysis
Several studies have investigated whether heterozygosity for a 32-basepair deletion in the CC chemokine receptor 5 gene (CCR5-Delta32 ) affects susceptibility to perinatal HIV-1 infection, but results have been inconclusive....
Analytic review of modeling studies of ARV Based PrEP interventions reveals strong influence of drug-resistance assumptions on the population-level effectiveness
BACKGROUND: Four clinical trials have shown that oral and topical pre-exposure prophylaxis (PrEP) based on tenofovir may be effective in preventing HIV transmission. The expected reduction in HIV transmission and...
