Category Archives: Prevention
The effectiveness of group-based comprehensive risk-reduction and abstinence education interventions to prevent or reduce the risk of adolescent pregnancy, human immunodeficiency virus, and sexually transmitted infections: Two systematic reviews
CONTEXT: Adolescent pregnancy, HIV, and other sexually transmitted infections (STIs) are major public health problems in the U.S. Implementing group-based interventions that address the sexual behavior of adolescents may reduce...
Vitamin supplementation for prevention of mother-to-child transmission of HIV and pre-term delivery: A systematic review of randomized trial including more than 2800 women
Background: Observational studies have suggested that low serum vitamin levels are associated with increased mother-to-child transmission (MTCT) of HIV and increased preterm delivery. We aimed to determine the efficacy of...
HIV-related stigma as a barrier to achievement of global PMTCT and maternal health goals: A review of the evidence
The global community has set goals of virtual elimination of new child HIV infections and 50 percent reduction in HIV-related maternal mortality by the year 2015. Although much progress has...
Integrating antiretroviral therapy into antenatal care and maternal and child health settings: a systematic review and meta-analysis
OBJECTIVE: To determine whether integrating antiretroviral therapy (ART) into antenatal care (ANC) and maternal and child health (MCH) clinics could improve programmatic and patient outcomes. METHODS: The authors systematically searched...
Efficacy of antiretroviral drugs in reducing mother-to-child transmission of HIV in Africa: A meta-analysis of published clinical trials
Antiretroviral drugs (ARVs) have been shown to be efficacious in decreasing mother-to-child transmission (MTCT) of HIV. A summary estimate of the efficacy of ARVs in reducing MTCT is important for...
A systematic review of published evidence on intervention impact on condom use in sub-Saharan Africa and Asia
OBJECTIVE: There has been much debate about the value of condoms in HIV/STI programming. This should be informed by evidence about intervention impact on condom use, but there is limited...
A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men
This meta-analysis examines the efficacy of international HIV prevention interventions designed to reduce sexual risk behavior of men who have sex with men (MSM). We performed a comprehensive search of...
Cost-effectiveness of community-level approaches to HIV prevention: A review
Effective community-level HIV prevention strategies have the potential to reach large numbers of at-risk individuals at relatively small per-capita costs, and therefore to be highly cost-effective. We review the published...
Economic costs of HIV/AIDS prevention activities in sub-Saharan Africa
This paper reviews the existing evidence base of the costs of prevention activities in sub-Saharan Africa, considers the degree of comparability between different cost estimates and highlights factors that are important in attempting...
