Category Archives: Prevention

The magnitude of loss to follow-up of HIV-exposed infants along the prevention of mother-to-child HIV transmission continuum of care: A systematic review and meta-analysis

2013

INTRODUCTION: Although prevention of mother-to-child HIV transmission (PMTCT) programs are widely implemented, many children do not benefit from them because of loss to follow-up (LTFU). We conducted a systematic review...

Adherence challenges with drugs for pre-exposure prophylaxis to prevent HIV infection

2014

Background There are 34 million people living with human immunodeficiency virus (HIV) worldwide and each year this number increases. Until a vaccine is discovered, the prevention of new HIV infections...

Male involvement for increasing the effectiveness of prevention of mother-to-child HIV transmission (PMTCT) programmes

2012

Despite efforts to increase the uptake of prevention of mother to child transmission of HIV (PMTCT) services, coverage is still lower than desired in developing countries. A lack of male...

A systematic review of the quality of trials evaluating biomedical HIV prevention interventions shows that many lack power

2009

Purpose: Several randomized, controlled trials (RCTs) have tested strategies to prevent sexual acquisition of HIV infection, but their quality has been variable. We aimed to identify, describe, and evaluate the...

The impact of Prevention of Mother to Child Transmission (PMTCT) programmes on maternal health care in resource-poor settings: Looking beyond the PMTCT programme – a systematic review

2010

BACKGROUND: There is increasing debate about the impact of scaled-up HIV/AIDS programmes on fragile healthcare systems in low-income countries. OBJECTIVES: To contribute to the understanding of the relation between HIV/AIDS...

Meta-analyses of seven of the National Institute on Drug Abuse’s principles of drug addiction treatment

2012

Of the 13 principles of drug addiction treatment disseminated by the National Institute on Drug Abuse (NIDA), 7 were meta-analyzed as part of the Evidence-based Principles of Treatment (EPT) project....

Secrets and safety in the age of AIDS: Does HIV disclosure lead to safer sex?

2004

To fuel the HIV/AIDS epidemic, HIV-seropositive individuals must interact unsafely with HIV-seronegative individuals. Research indicates that up to one third of individuals diagnosed with HIV continue to have unprotected sex,...

Interventions to reduce sexual risk for the human immunodeficiency virus in adolescents, 1985-2000: A research synthesis

2003

OBJECTIVE: To summarize studies that have tested the efficacy of human immunodeficiency virus (HIV) sexual risk-reduction interventions in adolescents. DATA SOURCES: Reports were gathered from computerized databases, by contacting individual...

Persuasive communications to change actions: An analysis of behavioral and cognitive impact in HIV prevention

2003

This meta-analysis examined the validity of various theoretical assumptions about cognitive and behavioral change following a communication recommending condom use. The synthesis comprised 82 treatment and 29 control groups included...

HIV/AIDS and mental health research in sub-Saharan Africa: A systematic review

2011

The relationship between mental illness and HIV/AIDS is complex and bidirectional. A significant amount of research has been performed in high-income countries but less is known about HIV and mental...

Prevention of sexual risk behavior for HIV infection with women

2000

This paper defines the components of gender-specific interventions for HIV infections for women, i.e. negotiation skills with male partners for condom use, integration of strategies against HIV and other STD...

Weighing the gold in the gold standard: Challenges in HIV prevention research

2010

OBJECTIVE(S): Few HIV prevention interventions have been evaluated in randomized controlled trials (RCTs). We examined design, implementation, and contextual considerations that may limit detection of a positive or adverse effect...

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