Category Archives: Prevention
Cytotoxic T-lymphocyte responses to canarypox vector-based HIV vaccines in HIV-seronegative individuals: A meta-analysis of published studies
PURPOSE: A successful prophylactic HIV vaccine will probably require neutralizing antibodies and vigorous CTL (CD8+ T-cytotoxic lymphocyte) responses. Canarypox vector-based HIV vaccines (ALVAC-HIV) have been gaining momentum as promising HIV...
Is there a role for primary care clinicians in providing shared care in HIV treatment? A systematic literature review
BACKGROUND: Despite HIV being increasingly considered as a chronic illness, there is as yet no consensus about how primary care should be integrated with specialty care to provide optimal clinical...
The evolving design and methods for trials evaluating the safety of candidate vaginal microbicides: A systematic review
Vaginal preexposure prophylaxis is a promising biomedical tool for HIV prevention. Although guidelines for the clinical assessment of microbicides are available, validated markers for product safety are lacking. To inform...
Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection
OBJECTIVE: To evaluate the efficacy of antiretroviral therapies in reducing the risk of mother-to-child transmission of HIV infection. METHODS: Systematic review and meta-analysis of randomized controlled trials. Clinical trials of...
Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA: A meta-analysis
BACKGROUND: We did a meta-analysis to assess factors associated with disparities in HIV infection in black men who have sex with men (MSM) in Canada, the UK, and the USA....
Protecting our militaries: A systematic literature review of military human immunodeficiency virus/acquired immunodeficiency syndrome prevention programs worldwide
OBJECTIVES: To systematically review published studies of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) prevention programs targeting the world’s military populations. METHODS: We systematically searched eight electronic databases (publications from...
Sexual risk reduction for HIV-infected persons: A meta-analytic review of “positive prevention” randomized clinical trials
BACKGROUND: Prevention intervention trials have been conducted to reduce risk of sexual transmission among people living with HIV/AIDS (PLWHA), but the findings were inconsistent. We performed a systematic review and...
Social network-based interventions to promote condom use: A systematic review
Effective sexually transmitted infection (STIs)/HIV prevention programs are urgently needed, but translating evidence-based methods of STI/HIV prevention into sustainable programs has been difficult. Social influences are critical for establishing condom...
