Category Archives: Prevention

Efficacy of HIV Prevention Interventions in Latin American and Caribbean Nations, 1995-2008: A Meta-Analysis

2010

This meta-analysis synthesized 37 HIV prevention interventions (from 28 studies) that were evaluated in Latin American and Caribbean nations. These studies were obtained through systematic searches of English, Spanish, and...

HIV risk behavior self-report reliability at different recall periods

2010

Few studies have investigated the optimal length of recall period for self-report of sex and drug-use behaviors. This meta-analysis of 28 studies examined the test-retest reliability of three commonly used...

School-based teenage pregnancy prevention programs: A systematic review of randomized controlled trials

2005

We compared school-based abstinence-only programs with those including contraceptive information (abstinence-plus) to determine which has the greatest impact on teen pregnancy. The United States has one of the highest rates...

Telephone delivered interventions for reducing morbidity and mortality in people with HIV infection

2013

Background: This is one of three Cochrane reviews examining the role of the telephone in HIV/AIDS services. Telephone interventions, delivered either by landline or mobile phone, may be useful in...

A systematic review to quantitatively evaluate ‘Stepping Stones’: A participatory community-based HIV/AIDS prevention intervention

2013

This first independent systematic review examined evidence for the effectiveness of the stepping stones intervention in HIV prevention. To reduce HIV transmission it addresses gender roles and promotes equitable relationships....

Interventions to modify sexual risk behaviours for preventing HIV in homeless youth

2011

BACKGROUND: Homeless youth are at high risk for HIV infection as a consequence of risky sexual behaviour. Interventions for homeless youth are challenging. Assessment of the effectiveness of interventions to...

Are needle and syringe programmes associated with a reduction in HIV transmission among people who inject drugs: A systematic review and meta-analysis

2014

BACKGROUND: Needle and syringe programmes (NSP) aim to reduce the risk of HIV by providing people who inject drugs (PWID) with sterile injecting equipment. A recent review of reviews (ROR)...

A systematic review of education for the prevention of HIV/AIDS among older adults

2012

Through a comprehensive literature search, the authors of this systematic review identified 21 articles focused on primary prevention of HIV/AIDS for adults aged 50 and over. Three major challenges to...

Cost-effectiveness of antenatal HIV-testing: Reviewing its pharmaceutical and methodological aspects

2004

This paper reviews the pharmacoeconomic aspects of antenatal testing for HIV. HIV is a retrovirus which is transmitted among humans through sexual contact, infected blood or blood products (needle sharing...

Effect of CCR5-delta32 heterozygosity on the risk of perinatal HIV-1 infection: A meta-analysis

2003

Several studies have investigated whether heterozygosity for a 32-basepair deletion in the CC chemokine receptor 5 gene (CCR5-Delta32 ) affects susceptibility to perinatal HIV-1 infection, but results have been inconclusive....

Analytic review of modeling studies of ARV Based PrEP interventions reveals strong influence of drug-resistance assumptions on the population-level effectiveness

2013

BACKGROUND: Four clinical trials have shown that oral and topical pre-exposure prophylaxis (PrEP) based on tenofovir may be effective in preventing HIV transmission. The expected reduction in HIV transmission and...

Vaginal microbicides for reducing the risk of sexual acquisition of HIV infection in women: Systematic review and meta-analysis

2012

BACKGROUND: Each year more than two million people are newly infected with HIV worldwide, a majority of them through unprotected vaginal sex. More than half of new infections in adults...

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