Category Archives: Prevention

A typology of HIV self-testing support systems: a scoping review

2024

To maximise the benefits of HIV self-testing (HIVST), it is critical to support self-testers in the testing process and ensure that they access appropriate prevention and care. To summarise systems...

Explaining inequity in knowledge, attitude, and services related to HIV/AIDS: A systematic review

2024

BACKGROUND: Equitable service provision and coverage are important responses to end the threat of the HIV/AIDS pandemic. Understanding inequity supports policies and programmes to deliver tailored interventions. There is continuous...

Engagement along the PrEP care continuum among men who have sex with men in China: A systematic review and meta-analysis

2024

Pre-exposure prophylaxis (PrEP), including daily oral, on-demand, and long-acting injectable (LAI), is a promising HIV prevention intervention for men who have sex with men (MSM). We conducted a systematic review...

Human immunodeficiency virus preexposure prophylaxis awareness and acceptability among men who have sex with men and transgender persons in India: Systematic review and meta-analysis

2024

With increasing importance being given to preexposure prophylaxis (PrEP) for human immunodeficiency virus prevention among men who have sex with men (MSM) and transgender persons (TG), we undertook a systematic...

Global prevalence and correlates of mpox vaccine acceptance and uptake: A systematic review and meta-analysis

2024

BACKGROUND: Vaccination has been recommended as one of the most potent ways of controlling the mpox (formerly, monkeypox) outbreak, particularly among high-risk groups. Here, we evaluated the prevalence of mpox...

Missed opportunities for guidance on sexually transmitted infection services: A global review of national HIV PrEP guidance

2024

OBJECTIVES: People who use or would benefit from pre-exposure prophylaxis (PrEP) for HIV infection are disproportionately affected by sexually transmitted infections (STIs). Integrating STI services when offering PrEP fosters synergies...

Barriers and facilitators to uptake and use of oral pre-exposure prophylaxis in pregnant and postpartum women: A qualitative meta-synthesis

2024

BACKGROUND: Acute HIV infection during pregnancy and in the postpartum period increases the risk of vertical transmission. The World Health Organization (WHO) has recommended preexposure prophylaxis for pregnant and postpartum...

Acceptability of a future HIV vaccine: A rapid scoping review

2024

BACKGROUND: A HIV vaccine is not available yet, but perceptions of HIV vaccines will be important to explore before their roll-out for effective vaccine promotion. This article presents the findings...

Sexual behavior among emerging adults in Africa: A systematic review and meta-analysis

2024

BACKGROUND: Estimates on sexual behavior (SB) among emerging adults (EmA) is varied in literature, which presents a challenge when designing targeted interventions. We aimed to summarize literature on prevalence and...

Pharmacovigilance in pregnancy studies, exposures and outcomes ascertainment, and findings from low- and middle-income countries: A scoping review

2024

Introduction Pharmacovigilance (PV), or the ongoing safety monitoring after a medication has been licensed, plays a crucial role in pregnancy, as clinical trials often exclude pregnant people. It is important...

Level of HIV serodiscordance and associated factors among heterosexual couples in Ethiopia: A systematic review and meta-analysis

2024

HIV-related causes accounted for approximately 770,000 deaths globally in 2018. Globally, there were 1.7 million new infections, and approximately 37.9 million people were living with HIV by the end of...

Clinical pharmacology considerations and drug-drug interactions with long-acting cabotegravir and rilpivirine relevant to sub-Saharan Africa

2024

Long-acting injectable (LAI) cabotegravir and rilpivirine for HIV treatment and LAI cabotegravir for pre-exposure HIV prophylaxis are being rolled out in a multitude of countries worldwide. Due to the prolonged...

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