Category Archives: Prevention

Minority stress and stimulant use among US adult sexual minority men: A systematic review

2025

Purpose Minority stress theory posits health disparities among sexual minority men (SMM; i.e., non-heterosexual) result from experiences of sexual minority stigma (SMS). This systematic review synthesizes quantitative findings on the...

Risk perception of human immunodeficiency virus, acquired immune deficiency syndrome, and reproductive health education among among junior and senior high school students: A scoping review

2025

This scoping review aims to identify studies that examine the existence and impact of HIV/AIDs education among high school-aged individuals in Ghana, underscoring the association of factors such as stigma...

Sexualized drug use (chemsex and methamphetamine) among men who have sex with men

2025

Key take-home messages

HIV post-exposure prophylaxis in community settings and by lay health workers or through task sharing: A systematic review of effectiveness, case studies, values and preferences, and costs

2025

INTRODUCTION: Post-exposure prophylaxis (PEP) for HIV prevention has been inadequately promoted, provided and used. Expanded access and task sharing could increase the HIV prevention impact of PEP, but scientific evidence...

User preferences on long-acting pre-exposure prophylaxis for HIV prevention in Eastern and Southern Africa: A scoping review

2025

BACKGROUND: Novel formulations for pre-exposure prophylaxis (PrEP) such as injectables, implants, and intravaginal rings are emerging as long-acting alternatives to daily pills for the prevention of HIV. Eastern and Southern...

A systematic review of T cell epitopes defined from the proteome of human immunodeficiency virus

2025

BACKGROUND: Human immunodeficiency virus (HIV) persists as a formidable and far – reaching threat without a cure. T cells are crucial for antiviral immunity and pathology in HIV patients, with...

Preferences for long-acting HIV pre-exposure prophylaxis among women of reproductive age in low- and middle-income countries: A systematic review

2025

HIV remains a major public health problem in low- and middle-income countries (LMICs). While oral pre-exposure prophylaxis (PrEP) is documented as safe and effective for HIV prevention, adherence remains a...

Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: A systematic review

2025

Background To stem rising fatal overdoses and other substance use/use disorder (SUD)-related harms, communities are turning to low-barrier harm reduction strategies, such as harm reduction-focused vending machines (VMs) that distribute...

Interventions to improve HIV care continuum outcomes for people with HIV who have incarceration experience: A narrative review

2025

People with HIV who are reentering the community after incarceration encounter multiple barriers to engagement in HIV care and treatment. We conducted a narrative review of recent interventions (2020-2023) developed...

Knowledge, attitudes, and willingness of healthcare workers to offer pre-exposure prophylaxis in Africa: A systematic review and meta-analysis

2025

Background Despite advancements in HIV prevention strategies, including pre-exposure prophylaxis (PrEP), uptake remains suboptimal in high-burden regions like Africa. Healthcare workers (HCWs) play a pivotal role in PrEP implementation. This...

Effects of test-and-treat versus preexposure prophylaxis on elimination of HIV transmission: Analysis of 24 HIV prevention trials

2025

INTRODUCTION: In 2023, 28.8 million (72%) of 39.9 million people with HIV (PWH) worldwide were on treatment with viral suppression, while 11.1 million (28%) people had viraemia with the risk...

Descriptions of risks and benefits of HIV vaccine trials in low-and middle-income countries (LMICs): An integrative review

2025

Human immunodeficiency virus (HIV) vaccine trials are needed in efforts to prevent infection and acquired immunodeficiency syndrome (AIDS). Like other types of research, HIV vaccine trials present benefits and risks...

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