Category Archives: Prevention
Immune checkpoint inhibitor therapy for cancer patients infected with HIV: A systematic review
BACKGROUND: Immune checkpoint inhibitor (ICI) therapy represents a breakthrough in cancer treatment. However, clinical trials of ICI have usually excluded people living with HIV (PLWH). The efficacy and safety data...
Characteristics of successful programmes targeting gender inequality and restrictive gender norms for the health and wellbeing of children, adolescents, and young adults: A systematic review
BACKGROUND: In the context of the Sustainable Development Goals and the shifting global burden of disease, this systematic review analyses the evidence from rigorously evaluated programmes that seek to transform...
Human immunodeficiency virus positive status disclosure to a sexual partner and its determinant factors in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to...
A systematic review and meta-analysis of interventions for orphans and vulnerable children affected by HIV/AIDS worldwide
BACKGROUND: Worldwide, there are more than 13.3 million orphans and vulnerable children affected by Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) (HIV OVC), defined as individuals below...
HIV/AIDS-knowledge and attitudes in the Arabian Peninsula: A systematic review and meta-analysis
BACKGROUND: HIV/AIDS prevention has been widely adopted worldwide, but little is known about HIV/AIDS knowledge and attitudes in the Arabian Peninsula. AIM: To summarize the level of knowledge and attitude...
A qualitative systematic review of cigarette smoking cessation interventions for persons living with HIV
Persons living with HIV (PLWH) have disproportionately high rates of both cigarette smoking and tobacco-induced negative health outcomes. The goal of this qualitative systematic review was to identify gaps in...
Attributes of HIV infection over decades (1982–2018): A systematic review and meta-analysis
Understanding the risk factors for HIV infection is the foundation of successful preventive strategies, which must bundle sociocultural, behavioural and biomedical interventions to halt disease transmission. We aimed in this...
The pharmacogenetics of efavirenz metabolism in children: The potential genetic and medical contributions to child development in the context of long-term ARV treatment
Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between...
