Category Archives: Prevention

Interventions to reduce social isolation and loneliness among men who have sex with men

2020

Key take-home messages Social isolation and loneliness are significantly associated with all-cause mortality in the general population. A recent study among gay and bisexual men who have sex with men...

Immune checkpoint inhibitor therapy for cancer patients infected with HIV: A systematic review

2020

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy represents a breakthrough in cancer treatment. However, clinical trials of ICI have usually excluded people living with HIV (PLWH). The efficacy and safety data...

Peer education for HIV prevention among high-risk groups: A systematic review and meta-analysis

2020

BACKGROUND: Peer education has become a strategy for health promotion among high-risk groups for HIV infection worldwide. However, the extent to which peer education could have an impact on HIV...

Characteristics of successful programmes targeting gender inequality and restrictive gender norms for the health and wellbeing of children, adolescents, and young adults: A systematic review

2020

BACKGROUND: In the context of the Sustainable Development Goals and the shifting global burden of disease, this systematic review analyses the evidence from rigorously evaluated programmes that seek to transform...

A scoping review on the role of masculine norms in men’s engagement in the HIV care continuum in sub-Saharan Africa

2019

Men living with HIV/AIDS in sub-Saharan Africa are less likely than women to be engaged at each stage of the HIV care continuum. We conducted a scoping review in May...

Human immunodeficiency virus positive status disclosure to a sexual partner and its determinant factors in Ethiopia: A systematic review and meta-analysis

2020

BACKGROUND: Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to...

A systematic review and meta-analysis of interventions for orphans and vulnerable children affected by HIV/AIDS worldwide

2020

BACKGROUND: Worldwide, there are more than 13.3 million orphans and vulnerable children affected by Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) (HIV OVC), defined as individuals below...

HIV/AIDS-knowledge and attitudes in the Arabian Peninsula: A systematic review and meta-analysis

2020

BACKGROUND: HIV/AIDS prevention has been widely adopted worldwide, but little is known about HIV/AIDS knowledge and attitudes in the Arabian Peninsula. AIM: To summarize the level of knowledge and attitude...

A qualitative systematic review of cigarette smoking cessation interventions for persons living with HIV

2019

Persons living with HIV (PLWH) have disproportionately high rates of both cigarette smoking and tobacco-induced negative health outcomes. The goal of this qualitative systematic review was to identify gaps in...

Attributes of HIV infection over decades (1982–2018): A systematic review and meta-analysis

2020

Understanding the risk factors for HIV infection is the foundation of successful preventive strategies, which must bundle sociocultural, behavioural and biomedical interventions to halt disease transmission. We aimed in this...

Interventions to improve medication adherence in adolescents with HIV: A systematic review and meta-analysis

2020

As of 2017, 1.8 million people living with HIV (PLWH) were adolescents between ages 10 and 19, accounting for 5% of all PLWH and 590,000 people between the ages 15...

The pharmacogenetics of efavirenz metabolism in children: The potential genetic and medical contributions to child development in the context of long-term ARV treatment

2020

Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between...

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