Category Archives: Prevention
Isoniazid preventive therapy plus antiretroviral therapy for the prevention of tuberculosis: A systematic review and meta-analysis of individual participant data
Background: Isoniazid preventive therapy prevents active tuberculosis in people with HIV, but previous studies have found no evidence of benefit in people with HIV who had a negative tuberculin skin...
The effects of HIV self-testing on the uptake of HIV testing, linkage to antiretroviral treatment and social harms among adults in Africa: A systematic review and meta-analysis
INTRODUCTION: HIV infection is still a global public health problem. More than 75% of HIV-infected people are in Africa, and up to 54% are unaware of their HIV status, limiting...
Sexual health interventions delivered to participants by mobile technology: A systematic review and meta-analysis of randomised controlled trials
Background: The use of mobile technologies to prevent STIs is recognised as a promising approach worldwide; however, evidence has been inconclusive, and the field has developed rapidly. With about 1...
An in-depth analysis of novel combinatorial drug therapy via nanocarriers against HIV/AIDS infection and their clinical perspectives: A systematic review
INTRODUCTION: Conventional antiretroviral therapy against HIV infections is threatening to become outdated due to the low chemical, physical, biological, and pharmacokinetic characteristics of therapeutic molecules, followed by the high chance...
Use of dating sites and applications by women and their risk of sexually transmitted infections: A systematic review and meta-analysis protocol
INTRODUCTION: The use of social networks has been increasing worldwide. Mobile websites and applications (apps) allow people to network more quickly and have more partners for sex. This can facilitate...
Understanding Mental Health in the Context of Adolescent Pregnancy and HIV in Sub-Saharan Africa: A Systematic Review Identifying a Critical Evidence Gap
Adolescent (10–19 years) mental health remains an overlooked global health issue. Rates of adolescent pregnancy within sub-Saharan Africa are some of the highest in the world and occur at the...
Pre-exposure prophylaxis care continuum, barriers, and facilitators among Black men who have sex with men in the United States: A systematic review and meta-analysis
Pre-exposure prophylaxis (PrEP) represents a viable HIV prevention tool for black men who have sex with men (BMSM). However, aggregated evidence regarding the presentations and determinants of the PrEP continuum...
Effectiveness of take-home naloxone programs and availability of naloxone nasal spray in different jurisdictions
Key take-home messages There is wide support of take-home naloxone programs as they are associated with decreased mortality, but there is some evidence that take-home naloxone alone may not be...
Measles seroprevalence and vaccine responses in human immunodeficiency virus-infected adolescents and adults: A systematic review
BACKGROUND: The World Health Organization (WHO) recommends an additional dose of measles-containing vaccine (MCV) for human immunodeficiency virus (HIV)-infected children receiving highly active antiretroviral therapy following immune reconstitution. We conducted...
Electronic and other new media technology interventions for HIV care and prevention: A systematic review
INTRODUCTION: Electronic and other new media technologies (eHealth) can facilitate large-scale dissemination of information and effective delivery of interventions for HIV care and prevention. There is a need to both...
Changes in smoking patterns after HIV diagnosis or antiretroviral treatment initiation: A global systematic review and meta-analysis
Abstract Background Tobacco consumption is more life-threatening in people living with human immunodeficiency virus (HIV) than within the general population; therefore, people living with HIV (PLWH) should be highly motivated...
