Category Archives: Prevention
Nature of, and responses to key sexual and reproductive health challenges for adolescents in urban slums in sub-Saharan Africa: A scoping review
BACKGROUND: Addressing adolescents’ sexual and reproductive health and rights (SRHR) requires an understanding of the socio-cultural and spatial settings within which they live. One setting of particular importance is the...
Interventions to improve HIV care continuum outcomes among individuals released from prison or jail: Systematic literature review
BACKGROUND: HIV care continuum outcomes deteriorate among people returning from incarceration. Interventions to improve care outcomes post-incarceration have been characterized by substantial heterogeneity in approach, outcome metrics, and results. A...
Community-based psychosocial substance use disorder interventions in low-and-middle-income countries: A narrative literature review
BACKGROUND: Mental health and substance use disorders (SUDs) are the world’s leading cause of years lived with disability; in low-and-middle income countries (LIMCs), the treatment gap for SUDs is at...
Diagnostic infectious diseases testing outside clinics: A global systematic review and meta-analysis
BACKGROUND: Most people around the world do not have access to facility-based diagnostic testing, and the gap in availability of diagnostic tests is a major public health challenge. Self-testing, self-sampling,...
Immunological and Psychological Efficacy of Meditation/Yoga Intervention Among People Living With HIV (PLWH): A Systematic Review and Meta-analyses of 19 Randomized Controlled Trials
BACKGROUND: An expanding number of mind-body therapies are being used to reduce the psychological burden of peoples living with human immunodeficiency virus (HIV). However, the effects on the immune system...
Effectiveness of interventions for adherence to antiretroviral therapy in adults with HIV: A systematic review
OBJECTIVE: To identify the best available evidence of intervention effectiveness for adherence to antiretroviral therapy for HIV in adults. METHOD: The methodology proposed by the Cochrane Collaboration was used, with...
Methadone maintenance therapy service components linked to improvements in HIV care cascade outcomes: A systematic review of trials and observational studies
BACKGROUND: The beneficial links between engagement in methadone maintenance therapy (MMT) and HIV treatment outcomes have been extensively described. Nevertheless, people who use drugs (PWUD) continue to experience suboptimal HIV...
Meta-synthesis of qualitative research of pre-exposure prophylaxis (PrEP) adherence among men who have sex with men (MSM)
The aim of the study was to consolidate evidence on barriers and facilitators to PrEP adherence among men who have sex with men. PubMed, Science Direct, and EBSCO host were...
Effect of vitamin D, selenium, or zinc supplementation in HIV: A systematic review
We conducted a systematic review to examine evidence from randomized controlled trials studying the effect of Vitamin D, selenium, or zinc supplementation in human immunodeficiency virus (HIV). An electronic literature...
The effect of successful antiretroviral therapy on immune activation and Reconstitution in HIV infected adults: A systematic review and meta-analysis
We performed a systematic review and meta-analysis to investigate the impact of antiretroviral therapy (ART) on immune activation and reconstitution in people living with human immunodeficiency virus (PLWH). The PubMed...
Summary of the NACI systematic review and recommendation on the use of live attenuated influenza vaccine (LAIV) in HIV-infected individuals
BACKGROUND: Annual influenza vaccination is recommended for all individuals six months of age and older, including those with HIV infection. Prior to this statement, the National Advisory Committee on Immunization...
