Category Archives: Prevention
Health literacy and health outcomes in persons living with HIV disease: A systematic review
Low health literacy is associated with challenges for those living with HIV including medication non-adherence and poorer health outcomes. The aim of this study was to systematically review the literature...
Substance use screening in HIV care settings: A review and critique of the literature
PURPOSE OF REVIEW: People living with human immunodeficiency virus/AIDS (PLWHA) experience high prevalence of substance use disorders (SUD). HIV care settings represent a unique opportunity to identify possible SUD, to...
Optimizing pediatric dosing recommendations and treatment management of antiretroviral drugs utilizing therapeutic drug monitoring data in children living with HIV
INTRODUCTION: This review summarises the current dosing recommendations for antiretroviral drugs (ARVs) in the international pediatric guidelines of the World Health Organisation (WHO), US Department of Health and Human Services...
Does male circumcision reduce women’s risk of sexually transmitted infections, cervical cancer, and associated conditions?
Background: Male circumcision (MC) is proven to substantially reduce men’s risk of a number of sexually transmitted infections (STIs). We conducted a detailed systematic review of the scientific literature to...
Retest and treat: A review of national HIV retesting guidelines to inform elimination of mother-to-child HIV transmission (EMTCT) efforts
INTRODUCTION: High maternal HIV incidence contributes substantially to mother-to-child HIV transmission (MTCT) in some settings. Since 2006, HIV retesting during the third trimester and breastfeeding has been recommended by the...
Sexual agreements: A scoping review of measurement, prevalence and links to health outcomes
A sexual agreement is a mutual understanding between two partners regarding sexual and relational behaviors both within and outside of their relationship. Sexual agreements have been central to research and...
Circumcision to prevent HIV and other sexually transmitted infections in men who have sex with men: A systematic review and meta-analysis of global data
BACKGROUND: Men who have sex with men (MSM) are disproportionately affected by HIV and other sexually transmitted infections (STIs) worldwide. Previous reviews investigating the role of circumcision in preventing HIV...
The impact of location on implementation of HIV/STI prevention interventions among LGBTQ communities
Key take-home messages The characteristics of a location, including segregation, community-level stigma, and infrastructural resources, may influence HIV service utilization and the HIV continuum of care among men who have...
A systematic review on the influence of HLA-B polymorphisms on HIV-1 mother-to-child transmission
BACKGROUND: Mother-to-child-transmission (MTCT) is the main route of HIV-1 infection in children. Genetic studies suggest HLA-B alleles play an important role on HIV-1 transmission, progression, and control of HIV-1 infection....
Integration of neonatal and child health interventions with pediatric HIV interventions in global health
Background/Objectives: In the last decade, many strategies have called for integration of HIV and child survival platforms to reduce missed opportunities and improve child health outcomes. Countries with generalized HIV...
A meta-analysis and systematic literature review of factors associated with sexual risk-taking during international travel
BACKGROUND: International travel facilitates global spread of sexually transmitted infections (STI). Travellers could contribute to onward transmission of pathogens rarely encountered at home and export new strains to the destination....
