Category Archives: Prevention
Stigma reduction interventions in people living with HIV to improve health-related quality of life
As the UNAIDS 90-90-90 targets for people living with HIV are increasingly being reached in many contexts, health-related quality of life, the so-called fourth 90, warrants special attention. HIV-related stigma...
Determinants of preterm birth among mothers who gave birth in East Africa: Systematic review and meta-analysis
BACKGROUND: Preterm birth (PTB) can be caused by different factors. The factors can be classified into different categories: socio demographic, obstetric, reproductive health, medical, behavioral and nutritional related. The objective...
A forgotten group during humanitarian crises: A systematic review of sexual and reproductive health interventions for young people including adolescents in humanitarian settings
Background: Young people including adolescents face barriers to healthcare and increased risk of poor sexual and reproductive health (SRH), which are exacerbated in humanitarian settings. Our systematic review assessed the...
Crowdsourcing methods to enhance HIV and sexual health services: A scoping review and qualitative synthesis
BACKGROUND: Crowdsourcing is increasingly used to improve community engagement in HIV and sexual health research. In this scoping review, we reviewed studies using crowdsourcing approaches in HIV and sexual health...
Economic compensation interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review and meta-analysis
BACKGROUND: Economic compensation interventions may help support higher voluntary medical male circumcision (VMMC) coverage in priority sub-Saharan African countries. To inform World Health Organization guidelines, we conducted a systematic review...
Use of an indeterminate range in HIV early infant diagnosis: A systematic review and meta-analysis
BACKGROUND: Expanded access to HIV antiretrovirals has dramatically reduced mother-to-child transmission of HIV. However, there is increasing concern around false-positive HIV test results in perinatally HIV-exposed infants but few insights...
Adjuvanted-influenza vaccination in patients infected with HIV: A systematic review and meta-analysis of immunogenicity and safety
Adjuvanted-influenza vaccination is an efficient method for enhancing the immunogenicity of influenza split-virus vaccines for preventing influenza. However, the medical community’s understanding of its performance in patients infected with HIV...
The impact, cost and cost-effectiveness of oral pre-exposure prophylaxis in sub-Saharan Africa: A scoping review of modelling contributions and way forward
INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) is a new form of HIV prevention being considered for inclusion in national prevention portfolios. Many mathematical modelling studies have been undertaken that speak to...
What will it take for the global plan priority countries in sub-Saharan Africa to eliminate mother-to-child transmission of HIV?
BACKGROUND: The 2016 ‘Start Free, Stay Free, AIDS Free’ global agenda, builds on the 2011-2015 ‘Global Plan’. It prioritises 22 countries where 90% of the world’s HIV-positive pregnant women live...
Adherence to HIV post-exposure prophylaxis for children/adolescents who have been sexually assaulted: A systematic review of barriers, enablers, and interventions
Post-exposure prophylaxis (PEP) is a key intervention for preventing HIV acquisition, including following sexual assault. However, uptake and completion rates for HIV PEP are lowest following sexual assault, with only...
Electronic health interventions to improve adherence to antiretroviral therapy in people living With HIV: Systematic review and meta-analysis
BACKGROUND: Electronic health (eHealth) is increasingly used for self-management and service delivery of HIV-related diseases. With the publication of studies increasingly focusing on antiretroviral therapy (ART) adherence, this makes it...
