Category Archives: Prevention
Undetectable = Untransmittable: A cross-population systematic review and meta-analysis on awareness and acceptance
The Undetectable = Untransmittable (U=U) message is a cornerstone of HIV-related public health communication, yet global levels of awareness and acceptance remain unclear across key populations. This study aimed to...
Immune responses to vaginal candidiasis in African women: A scoping review of cytokine profiles, T-cell activation, and gene expression
Background Recent immunological studies of vaginal candidiasis in African populations have revealed complex host‒pathogen interactions with implications for therapeutic development and HIV acquisition risk. Objective This scoping review synthesized evidence...
Adolescents’ sexual health during the COVID-19 outbreak: A systematic review
BACKGROUND AND AIMS: The COVID-19 pandemic has greatly disrupted adolescents’ access to sexual health services, resulting in a decline in their overall sexual well-being. This systematic review explored adolescent sexual...
Efficacy, immunogenicity, and safety of the Novavax COVID-19 vaccine in immunocompromised patients: A targeted literature review
Individuals who are immunocompromised (IIC) may have impaired infection prevention/resolution, potentially causing increased disease severity, complications, and healthcare-system strain. Exclusion of IIC from COVID-19 vaccine trials and limited real-world Novavax...
Pneumocystis infection in pregnant women: A scoping review
Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia in immunosuppressed individuals. While Pneumocystis colonization, a subclinical form of infection, has been studied in different populations, its implications during...
Technology-assisted interventions in the delivery of HIV prevention, care, and treatment services in sub-Saharan Africa: Scoping review
BACKGROUND: Sub-Saharan Africa (SSA) accounts for up to 67% of the global HIV burden yet grapples with health system challenges like distant health facilities, low doctor-to-patient ratio, and poor or...
Use of behavior change techniques in digital HIV prevention programs for adolescents and young people: Systematic review
BACKGROUND: HIV infections have caused severe public health and economic burdens to the world. Adolescents and young people continue to constitute a large proportion of newly diagnosed HIV cases. Digital...
Effectiveness of digital health interventions in promoting the pre-exposure prophylaxis (PrEP) care continuum among men who have sex with men (MSM): A systematic review of randomized controlled trials
PURPOSE OF REVIEW: Digital health interventions have demonstrated great potential to advance HIV prevention and care. However, their effectiveness in improving the pre-exposure prophylaxis (PrEP) care continuum has not yet...
