Category Archives: Biomedical interventions
Neuropsychiatric adverse events in tenofovir disoproxil fumarate- and tenofovir alafenamide-based HIV therapy and prophylaxis: A systematic review and meta-analysis
INTRODUCTION: Tenofovir is integral to antiretroviral therapy (ART) and preexposure prophylaxis (PrEP) for HIV, but its neuropsychiatric adverse events (NPAEs) have not been systematically investigated. OBJECTIVES: This systematic review aims...
Doxycycline post-exposure prophylaxis for bacterial sexually transmitted infections: The current landscape and future directions
PURPOSE OF REVIEW: The incidence of bacterial sexually transmitted infections (STI) continues to rise particularly among men who have sex with men (MSM). Doxycycline post-exposure prophylaxis (doxy-PEP) has emerged as...
Overview of hepatitis B vaccine non-response and associated B cell amnesia: A scoping review
BACKGROUND: The advent of the hepatitis B vaccine has achieved tremendous success in eradicating and reducing the burden of hepatitis B infection, which is the main culprit for hepatocellular carcinoma-one...
A systematic review of factors associated with COVID-19 vaccine uptake, hesitancy, and acceptability among adults with HIV: Implications for integrating COVID-19 immunization into HIV care
The COVID-19 virus, once a public health emergency, is now endemic. Immunization remains an important measure for mitigating high levels of disease, morbidity, and mortality related to COVID-19 infection. People...
Effectiveness of MenB-4C vaccine against gonorrhea: A systematic review and meta-analysis
Introduction: There is no licensed vaccine against gonorrhea but Neisseria meningitidis serogroup B outer membrane vesicle-based vaccines, like MenB-4C, may offer cross-protection against gonorrhea. This systematic review and meta-analysis synthesized...
Barriers and facilitators along the PrEP continuum of care among Latinx sexual minoritized men and transgender women: A systematic review
Latinx cisgender sexually minoritized men (SMM) and transgender women (TW) in the U.S. are disproportionately affected by HIV. Although pre-exposure prophylaxis (PrEP) is a highly effective strategy for HIV prevention,...
Intimate partner violence and HIV pre-exposure prophylaxis care engagement among sexual minority men: A systematic review
Sexual minority men (SMM) who experience intimate partner violence (IPV) may also be at increased risk for HIV; however, little is known about the relationship between these experiences and the...
Willingness to receive mpox vaccine among men who have sex with men: A systematic review and meta-analysis
Background Since May 2022, mpox outbreaks have been occurring in non-mpox endemic areas, with the main population affected being men who have sex with men (MSM). Outbreak prevention and control...
HIV PrEP coverage among Black adults: A concept analysis of the inequities, disparities, and implications
BACKGROUND: Significant racial disparities exist in HIV pre-exposure prophylaxis (PrEP) coverage in the United States (U.S), with Black individuals experiencing seven times higher new HIV infection rates compared to their...
The association between social support and pre-exposure prophylaxis use among sexual minority men in the United States: A scoping literature review
Sexual minority men (SMM) are disproportionately affected by HIV. Although pre-exposure prophylaxis (PrEP) is an effective way of reducing HIV incidence, PrEP use has remained relatively low. Social support may...
Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation
HIV/AIDS remains one of the world’s most significant public health and economic challenges, with approximately 36 million people currently living with the disease. Considerable progress has been made to reduce...
