Category Archives: Biomedical interventions
Decade of research into the acceptability of interventions aimed at improving adolescent and youth health and social outcomes in Africa: A systematic review and evidence map
OBJECTIVE: Interventions aimed at improving adolescent health and social outcomes are more likely to be successful if the young people they target find them acceptable. However, no standard definitions or...
Reproductive justice in the time of COVID-19: A systematic review of the indirect impacts of COVID-19 on sexual and reproductive health
OBJECTIVE: Despite gendered dimensions of COVID-19 becoming increasingly apparent, the impact of COVID-19 and other respiratory epidemics on women and girls’ sexual and reproductive health (SRH) have yet to be...
HIV-1 genetic diversity a challenge for AIDS vaccine development: A retrospective bibliometric analysis
Background: Despite recent advances in human immunodeficiency virus-1 (HIV-1) prevention, a fast, safe, and effective vaccine will probably be necessary to end the HIV/AIDS pandemic. This study was conducted to evaluate...
Awareness and sse of post-exposure prophylaxis for HIV prevention among men who have sex with men: A systematic review and meta-analysis
Background: The use of post-exposure prophylaxis (PEP) is effective in reducing HIV risk, but it is underused by men who have sex with men (MSM) due to certain psychological and...
The cost-effectiveness of HIV/STI prevention in high-income countries with concentrated epidemic settings: A scoping review
The purpose of this scoping review is to establish the state of the art on economic evaluations in the field of HIV/STI prevention in high-income countries with concentrated epidemic settings...
Acceptability of HIV pre-exposure prophylaxis in China: A systematic review and meta-analysis
Using pre-exposure prophylaxis (PrEP) for the prevention of HIV infection is a popular, contemporary research topic. We retrieved PubMed, Web of Science, MEDLINE, Wanfang, CNKI, and Sinomed databases, and related...
Where are the pregnant and breastfeeding women in new pre-exposure prophylaxis trials? The imperative to overcome the evidence gap
Pregnant and breastfeeding populations are at substantial risk of acquiring HIV in some settings, yet are underrepresented in clinical trials of new pre-exposure prophylaxis (PrEP) agents. Several PrEP formulations are...
Risk of vertical transmission of chronic viral infections after invasive prenatal procedures
OBJECTIVES: Invasive prenatal procedures including amniocentesis, chorionic villus sampling (CVS) can be prenatally indicated for diagnostic purposes. Chronic viral infections with Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), hepatitis...
A systematic review of linkage-to-care and antiretroviral initiation implementation strategies in low- and middle-income countries across sub-Saharan Africa
Linkage to care (LTC) and initiation of antiretroviral therapy (ART) are key components in the longitudinal care cascade for people living with HIV. Many strategies to optimize these stages of...
Characterizing the role of intersecting stigmas and sustained inequities in driving HIV syndemics across low-to-middle-income settings
PURPOSE OF REVIEW: In 2020, key populations around the world still have disproportionate risks for HIV acquisition and experiencing HIV-related syndemics. This review presents current data around HIV-related syndemics among...
