Category Archives: Biomedical interventions
An in-depth analysis of novel combinatorial drug therapy via nanocarriers against HIV/AIDS infection and their clinical perspectives: A systematic review
INTRODUCTION: Conventional antiretroviral therapy against HIV infections is threatening to become outdated due to the low chemical, physical, biological, and pharmacokinetic characteristics of therapeutic molecules, followed by the high chance...
Understanding Mental Health in the Context of Adolescent Pregnancy and HIV in Sub-Saharan Africa: A Systematic Review Identifying a Critical Evidence Gap
Adolescent (10–19 years) mental health remains an overlooked global health issue. Rates of adolescent pregnancy within sub-Saharan Africa are some of the highest in the world and occur at the...
Measles seroprevalence and vaccine responses in human immunodeficiency virus-infected adolescents and adults: A systematic review
BACKGROUND: The World Health Organization (WHO) recommends an additional dose of measles-containing vaccine (MCV) for human immunodeficiency virus (HIV)-infected children receiving highly active antiretroviral therapy following immune reconstitution. We conducted...
Effectiveness of take-home naloxone programs and availability of naloxone nasal spray in different jurisdictions
Key take-home messages There is wide support of take-home naloxone programs as they are associated with decreased mortality, but there is some evidence that take-home naloxone alone may not be...
Emerging evidence from a systematic review of safety of pre-exposure prophylaxis for pregnant and postpartum women: Where are we now and where are we heading?
INTRODUCTION: HIV incidence is high during pregnancy and breastfeeding with HIV acquisition risk more than doubling during pregnancy and the postpartum period compared to when women are not pregnant. The...
Electronic and other new media technology interventions for HIV care and prevention: A systematic review
INTRODUCTION: Electronic and other new media technologies (eHealth) can facilitate large-scale dissemination of information and effective delivery of interventions for HIV care and prevention. There is a need to both...
Health care provider barriers to HIV pre-exposure prophylaxis in the United States: A systematic review
Increasing prescription of pre-exposure prophylaxis (PrEP) is imperative to ending the HIV epidemic in the United States. The objective of this review was to identify health care provider barriers to...
Chronic kidney disease among human immunodeficiency virus positive patients on antiretroviral therapy in sub-Saharan Africa: A systematic review and meta-analysis
Human immunodeficiency virus (HIV)-infected patients are at risk for renal disease as a consequence of complications of antiretroviral treatment. Particularly, the complication of kidney disease is high in patients who...
A cascade of interventions to promote adherence to antiretroviral therapy in African countries
PURPOSE OF REVIEW: We reviewed interventions to improve uptake and adherence to antiretroviral therapy (ART) in African countries in the Treat All era. RECENT FINDINGS: ART initiation can be improved...
Sexually transmitted infections in pregnancy: A narrative review of the global research gaps, challenges, and opportunities
BACKGROUND: Sexually transmitted infections (STI), such as chlamydial, gonorrheal, and trichomonal infection, are prevalent in pregnant women in many countries and are widely reported to be associated with increased risk...
Cognitive and educational interventions for orphans and vulnerable children affected by HIV/AIDS: A meta-analysis
Orphans and vulnerable children affected by HIV/AIDS (HIV OVC) are at risk for cognitive difficulties and lack of access to education. Interventions addressing cognitive or educational outcomes for HIV OVC...
