Category Archives: Biomedical interventions
Attrition of HIV-exposed infants from early infant diagnosis services in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: Identification and retention of HIV-exposed infants in early infant diagnosis (EID) services helps to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition from...
Economic evaluations of pre- and post-exposure prophylaxis for HIV
Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...
Integration of neonatal and child health interventions with pediatric HIV interventions in global health
Background/Objectives: In the last decade, many strategies have called for integration of HIV and child survival platforms to reduce missed opportunities and improve child health outcomes. Countries with generalized HIV...
Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review
Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...
Male partner involvement in the utilization of hospital delivery services by pregnant women living with HIV in sub Saharan Africa: A systematic review and meta-analysis
Objective The level of male partner involvement in hospital delivery by pregnant women living with HIV in sub Saharan Africa (SSA) is low. We conducted a systematic review and meta-analysis...
Elimination of HIV transmission through novel and established prevention strategies among people who inject drugs
Despite the effectiveness of existing HIV prevention strategies for people who inject drugs (PWID), uncontrolled outbreaks of HIV among this group are common and occur around the world. In this...
Gay men’s attitudes towards and perceptions of viral load and treatment as prevention
Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...
Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV
Key take-home messages Oral PrEP (tenofovir disoproxil fumarate with emtricitabine) is highly protective against HIV acquisition across various populations and across different dosing schedules. Open label and demonstration projects in...
A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis
Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...