Category Archives: Biomedical interventions

Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review

2019

Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...

Male partner involvement in the utilization of hospital delivery services by pregnant women living with HIV in sub Saharan Africa: A systematic review and meta-analysis

2019

Objective The level of male partner involvement in hospital delivery by pregnant women living with HIV in sub Saharan Africa (SSA) is low. We conducted a systematic review and meta-analysis...

Effectiveness and cost-effectiveness of pre- & post-exposure prophylaxis for HIV

2010

Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...

Psychosocial support programs for HIV-positive women who are pregnant

2011

Key take-home messages Pregnant women with HIV have distinct psychosocial needs that must be addressed. Very little research has investigated the most effective means of delivering psychosocial support to pregnant...

Female condom use for men who have sex with men

2013

Key take-home messages Men who have sex with men who have used a female condom often complain of irritation, bunching up, unpleasant texture, noise, discomfort upon insertion, lack of pleasure,...

Gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)

2013

Key take-home messages There were fewer studies published on the potential use of non-occupational PEP (nPEP) among men who have sex with men than those on PrEP. Although 47% to...

Gay men’s attitudes towards and perceptions of viral load and treatment as prevention

2014

Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...

Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV

2018

Key take-home messages Oral PrEP (tenofovir disoproxil fumarate with emtricitabine) is highly protective against HIV acquisition across various populations and across different dosing schedules. Open label and demonstration projects in...

A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis

2018

Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...

Quality of HIV websites with information about pre-exposure prophylaxis or treatment as prevention for men who have sex with men: A systematic evaluation

2018

BACKGROUND: Knowledge and uptake of high-efficacy HIV prevention strategies such as pre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) remain low among men who have sex with men (MSM) who...

A review of approaches used to increase awareness of pre-exposure prophylaxis (PrEP) in the United States

2018

PrEP is an important and useful HIV prevention strategy, yet awareness remains low among at-risk populations in the United States and elsewhere in the world. As previous studies have shown...

Efficacy and safety of oral TDF-based pre-exposure prophylaxis for men who have sex with men: A systematic review and meta-analysis

2018

Background: Pre-exposure prophylaxis (PrEP) is used as an HIV prevention method by people at substantial risk of HIV infection. This systematic review and meta-analysis evaluates current clinical evidence for use...

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