Category Archives: Biomedical interventions
Forming and implementing community advisory boards in low- and middle-income countries: A scoping review
BACKGROUND: Community advisory boards (CABs) have expanded beyond high-income countries (HICs) and play an increasing role in low- and middle-income country (LMIC) research. Much research has examined CABs in HICs,...
Use of an indeterminate range in HIV early infant diagnosis: A systematic review and meta-analysis
BACKGROUND: Expanded access to HIV antiretrovirals has dramatically reduced mother-to-child transmission of HIV. However, there is increasing concern around false-positive HIV test results in perinatally HIV-exposed infants but few insights...
Adjuvanted-influenza vaccination in patients infected with HIV: A systematic review and meta-analysis of immunogenicity and safety
Adjuvanted-influenza vaccination is an efficient method for enhancing the immunogenicity of influenza split-virus vaccines for preventing influenza. However, the medical community’s understanding of its performance in patients infected with HIV...
The effectiveness of demand creation interventions for voluntary male medical circumcision for HIV prevention in sub-Saharan Africa: A mixed methods systematic review
INTRODUCTION: UNAIDS has recommended that in 14 countries across sub-Saharan Africa (SSA), 90% of men aged 10 to 29 years should be circumcised by 2021 to help reduce transmission of...
Pre-exposure prophylaxis for HIV prevention in women: Current status and future directions
Pre-exposure prophylaxis (PrEP) is a promising intervention to prevent HIV acquisition, with benefits both to the individual and to population-level health. PrEP is an opportunity to complement ongoing public health...
Suboptimal HIV pre-exposure prophylaxis awareness and willingness to use among women who use drugs in the United States: A systematic review and meta-analysis
In the United States (U.S.), more than 12 million women reported illicit drug use in the past month. Drug use has been linked to increased risk for HIV, but little...
Pre-exposure prophylaxis use and medication adherence among men who have sex with men: A systematic review of the literature
The appropriate use of pre-exposure prophylaxis (PrEP) by men who have sex with men (MSM) can be highly effective at reducing HIV transmission. Our review examined prevalence estimates, sexual behaviors,...
Cost-effectiveness of HIV prevention interventions in sub-Saharan Africa: A systematic review
Background: Sub-Saharan Africa carries the highest HIV burden globally. It is important to understand how interventions cost-effectively fit within guidelines and implementation plans, especially in low- and middle-income settings. We reviewed...
Factors affecting pre-exposure prophylaxis implementation for women in the United States: A systematic review
Oral HIV pre-exposure prophylaxis (PrEP) is a highly effective pill that HIV-negative individuals can take once daily to prevent HIV infection. Although PrEP is a private, user-controlled method that empowers...
A realist review of infant feeding counselling to increase exclusive breastfeeding by HIV-positive women in sub Saharan-Africa: What works for whom and in what contexts
BACKGROUND: The most recent World Health Organization (WHO) guidelines on Human Immunodeficiency Virus (HIV) and infant feeding promotes exclusive breastfeeding (EBF) in resource limited settings for the prevention of mother...
